8FZQ

Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)

Summary for 8FZQ

Entry DOI	10.2210/pdb8fzq/pdb
EMDB information	29637
Descriptor	Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	ion channel, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	169922.03
Authors	Levring, J.,Terry, D.S.,Kilic, Z.,Fitzgerald, G.A.,Blanchard, S.C.,Chen, J. (deposition date: 2023-01-29, release date: 2023-03-29, Last modification date: 2023-05-03)
Primary citation	Levring, J.,Terry, D.S.,Kilic, Z.,Fitzgerald, G.,Blanchard, S.,Chen, J. CFTR function, pathology and pharmacology at single-molecule resolution. Nature, 616:606-614, 2023 Cited by PubMed: 36949202 DOI: 10.1038/s41586-023-05854-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.3 Å)

Structure validation