8FZQ
Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystic fibrosis transmembrane conductance regulator | polymer | 1489 | 168859.1 | 1 | UniProt (P13569) Pfam (PF00664) Pfam (PF00005) Pfam (PF14396) | Homo sapiens (human) | CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, E (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence modifications
A: 1 - 1480 (UniProt: P13569)
| PDB | External Database | Details |
|---|---|---|
| Unk 751 | Arg 751 | conflict |
| Unk 752 | Ile 752 | conflict |
| Unk 753 | Ser 753 | conflict |
| Unk 754 | Val 754 | conflict |
| Unk 755 | Ile 755 | conflict |
| Unk 756 | Ser 756 | conflict |
| Unk 757 | Thr 757 | conflict |
| Unk 758 | Gly 758 | conflict |
| Unk 759 | Pro 759 | conflict |
| Unk 760 | Thr 760 | conflict |
| Unk 761 | Leu 761 | conflict |
| Unk 762 | Gln 762 | conflict |
| Unk 763 | Ala 763 | conflict |
| Unk 764 | Arg 764 | conflict |
| Unk 765 | Arg 765 | conflict |
| Unk 766 | Arg 766 | conflict |
| Unk 767 | Gln 767 | conflict |
| Unk 768 | Ser 768 | conflict |
| Unk 769 | Val 769 | conflict |
| Ser 1481 | - | expression tag |
| Asn 1482 | - | expression tag |
| Ser 1483 | - | expression tag |
| Leu 1484 | - | expression tag |
| Glu 1485 | - | expression tag |
| Val 1486 | - | expression tag |
| Leu 1487 | - | expression tag |
| Phe 1488 | - | expression tag |
| Gln 1489 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 168859.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 169922.0 |
