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2IDO
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BU of 2ido by Molmil
Structure of the E. coli Pol III epsilon-Hot proofreading complex
分子名称: 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ...
著者Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C.
登録日2006-09-15
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006
1U59
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BU of 1u59 by Molmil
Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine
分子名称: STAUROSPORINE, Tyrosine-protein kinase ZAP-70
著者Jin, L, Pluskey, S, Petrella, E.C, Cantin, S.M, Gorga, J.C, Rynkiewicz, M.J, Pandey, P, Strickler, J.E, Babine, R.E, Weaver, D.T, Seidl, K.J.
登録日2004-07-27
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS
J.Biol.Chem., 279, 2004
4D1E
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BU of 4d1e by Molmil
THE CRYSTAL STRUCTURE OF HUMAN MUSCLE ALPHA-ACTININ-2
分子名称: ALPHA-ACTININ-2
著者Pinotsis, N, Salmazo, A, Sjoeblom, B, Gkougkoulia, E, Djinovic-Carugo, K.
登録日2014-05-01
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The Structure and Regulation of Human Muscle Alpha-Actinin
Cell(Cambridge,Mass.), 159, 2014
5D5M
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BU of 5d5m by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, ACETATE ION, Beta-2-microglobulin, ...
著者Keller, A.N, Birkinshaw, R.W, Rossjohn, J.
登録日2015-08-11
公開日2016-01-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
3SH0
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BU of 3sh0 by Molmil
Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065
分子名称: 2-(dodecyloxy)-6-hydroxybenzoic acid, Undecaprenyl pyrophosphate synthase
著者Cao, R, Liu, Y.-L, Oldfield, E.
登録日2011-06-15
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
6Z3T
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BU of 6z3t by Molmil
Structure of canine Sec61 inhibited by mycolactone
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ...
著者Gerard, S.F, Higgins, M.K.
登録日2020-05-21
公開日2020-07-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structure of the Inhibited State of the Sec Translocon.
Mol.Cell, 79, 2020
4WA9
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BU of 4wa9 by Molmil
The crystal structure of human abl1 wild type kinase domain in complex with axitinib
分子名称: AXITINIB, Tyrosine-protein kinase ABL1
著者Johnson, E, McTigue, M, Cronin, C.N.
登録日2014-08-28
公開日2015-02-11
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.
Nature, 519, 2015
2ITM
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BU of 2itm by Molmil
Crystal structure of the E. coli xylulose kinase complexed with xylulose
分子名称: AMMONIUM ION, D-XYLULOSE, SULFATE ION, ...
著者di Luccio, E, Voegtli, J, Wilson, D.K.
登録日2006-10-19
公開日2006-11-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and kinetic studies of induced fit in xylulose kinase from Escherichia coli.
J.Mol.Biol., 365, 2007
2IV2
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BU of 2iv2 by Molmil
Reinterpretation of reduced form of formate dehydrogenase H from E. coli
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, Formate dehydrogenase H, GUANYLATE-O'-PHOSPHORIC ACID MONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,5,6,7,8A,9,10,10A-OCTAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL) ESTER, ...
著者Raaijmakers, H.C.A, Romao, M.J.
登録日2006-06-08
公開日2006-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Formate-Reduced E. Coli Formate Dehydrogenase H: The Reinterpretation of the Crystal Structure Suggests a New Reaction Mechanism.
J.Biol.Inorg.Chem., 11, 2006
6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
登録日2017-11-08
公開日2018-01-17
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
1U94
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BU of 1u94 by Molmil
Crystal Structure of E. Coli RecA in a Compressed Helical Filament Form 2
分子名称: CALCIUM ION, RecA protein
著者Xing, X, Bell, C.E.
登録日2004-08-09
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of Escherichia coli RecA in a compressed helical filament.
J.Mol.Biol., 342, 2004
8HJU
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BU of 8hju by Molmil
Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 10,000 lux
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ...
著者Xu, X, Xin, J.
登録日2022-11-23
公開日2023-09-20
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture.
Elife, 12, 2023
8HI1
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BU of 8hi1 by Molmil
Streptococcus thermophilus Cas1-Cas2- prespacer ternary complex
分子名称: CRISPR-associated endonuclease Cas1, DNA (26-MER), DNA (31-MER), ...
著者Chen, Q, Luo, Y.
登録日2022-11-18
公開日2023-09-13
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献DnaQ mediates directional spacer acquisition in the CRISPR-Cas system by a time-dependent mechanism.
Innovation (N Y), 4, 2023
4CKK
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BU of 4ckk by Molmil
Apo structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit
分子名称: DNA GYRASE SUBUNIT A
著者Hearnshaw, S.J, Edwards, M.J, Stevenson, C.E.M, Lawson, D.M, Maxwell, A.
登録日2014-01-07
公開日2014-03-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight Into the Mechanism of Inhibition.
J.Mol.Biol., 426, 2014
2HZA
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BU of 2hza by Molmil
Nickel-bound full-length Escherichia coli NikR
分子名称: 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, NICKEL (II) ION, Nickel-responsive regulator
著者Schreiter, E.R, Drennan, C.L.
登録日2006-08-08
公開日2006-08-22
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NikR-operator complex structure and the mechanism of repressor activation by metal ions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6YF2
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BU of 6yf2 by Molmil
FKBP12 in complex with the BMP potentiator compound 6 at 1.03A resolution
分子名称: (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-23,25-dimethoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14-bis(oxidanyl)-17-(2-oxidanylidenepropyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone, CADMIUM ION, CHLORIDE ION, ...
著者Kallen, J.
登録日2020-03-25
公開日2021-03-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Cell Chem Biol, 28, 2021
6YF3
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BU of 6yf3 by Molmil
FKBP12 in complex with the BMP potentiator compound 10 at 1.00A resolution
分子名称: (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14,23-tris(oxidanyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone, CADMIUM ION, CHLORIDE ION, ...
著者Kallen, J.
登録日2020-03-25
公開日2021-03-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Cell Chem Biol, 28, 2021
2VHJ
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BU of 2vhj by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, NTPASE P4
著者Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R.
登録日2007-11-21
公開日2007-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor.
J.Biol.Chem., 283, 2008
4UZL
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BU of 4uzl by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I MYRISTOLEATE COMPLEX - 2.1A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Myristoleic acid, PROTEIN NOTUM HOMOLOG
著者Zebisch, M, Jones, E.Y.
登録日2014-09-05
公開日2015-02-25
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
2I6R
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BU of 2i6r by Molmil
Crystal structure of E. coli HypE, a hydrogenase maturation protein
分子名称: HypE protein
著者Rangarajan, E.S, Proteau, A, Iannuzzi, P, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2006-08-29
公開日2007-10-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.
J.Bacteriol., 190, 2008
3S2Y
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BU of 3s2y by Molmil
Crystal structure of a chromate/uranium reductase from Gluconacetobacter hansenii
分子名称: CHLORIDE ION, Chromate reductase, FLAVIN MONONUCLEOTIDE, ...
著者Jin, H, Zhang, Y, Buchko, G.W, Li, P, Squier, T.C, Robinson, H, Varnum, S.M, Long, P.E.
登録日2011-05-17
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Structure Determination and Functional Analysis of a Chromate Reductase from Gluconacetobacter hansenii.
Plos One, 7, 2012
2VHT
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BU of 2vht by Molmil
P4 PROTEIN FROM BACTERIOPHAGE PHI12 R279A mutant in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, NTPASE P4
著者Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R.
登録日2007-11-25
公開日2007-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor.
J.Biol.Chem., 283, 2008
3CX2
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BU of 3cx2 by Molmil
Crystal structure of the C1 domain of cardiac isoform of myosin binding protein-C at 1.3A
分子名称: Myosin-binding protein C, cardiac-type
著者Fisher, S.J, Helliwell, J.R, Khurshid, S, Govada, L, Redwood, C, Squire, J.M, Chayen, N.E.
登録日2008-04-23
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An investigation into the protonation states of the C1 domain of cardiac myosin-binding protein C
Acta Crystallogr.,Sect.D, 64, 2008
1TOR
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BU of 1tor by Molmil
MOLECULAR DYNAMICS SIMULATION FROM 2D-NMR DATA OF THE FREE ACHR MIR DECAPEPTIDE AND THE ANTIBODY-BOUND [A76]MIR ANALOGUE
分子名称: ACETYLCHOLINE RECEPTOR, MAIN IMMUNOGENIC REGION
著者Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T.
登録日1995-10-11
公開日1996-03-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data.
Biopolymers, 40, 1996
8ACW
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BU of 8acw by Molmil
X-ray structure of Na+-NQR from Vibrio cholerae at 3.4 A resolution
分子名称: DODECYL-BETA-D-MALTOSIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Fritz, G.
登録日2022-07-07
公開日2023-07-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Conformational coupling of redox-driven Na + -translocation in Vibrio cholerae NADH:quinone oxidoreductase.
Nat.Struct.Mol.Biol., 30, 2023

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