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3SH0

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065

Summary for 3SH0
Entry DOI10.2210/pdb3sh0/pdb
Related3SGT 3SGV 3SGX
DescriptorUndecaprenyl pyrophosphate synthase, 2-(dodecyloxy)-6-hydroxybenzoic acid (3 entities in total)
Functional Keywordsalpha/beta, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight57929.57
Authors
Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2011-06-15, release date: 2012-12-19, Last modification date: 2023-09-13)
Primary citationZhu, W.,Zhang, Y.,Sinko, W.,Hensler, M.E.,Olson, J.,Molohon, K.J.,Lindert, S.,Cao, R.,Li, K.,Wang, K.,Wang, Y.,Liu, Y.L.,Sankovsky, A.,de Oliveira, C.A.,Mitchell, D.A.,Nizet, V.,McCammon, J.A.,Oldfield, E.
Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110:123-128, 2013
Cited by
PubMed: 23248302
DOI: 10.1073/pnas.1219899110
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.84 Å)
Structure validation

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