3SGT
Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1299
Summary for 3SGT
Entry DOI | 10.2210/pdb3sgt/pdb |
Descriptor | Undecaprenyl pyrophosphate synthase, 2-{[4-(3,4-dimethylphenoxy)phenyl]carbamoyl}benzoic acid (3 entities in total) |
Functional Keywords | alpha/beta, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Escherichia coli O6 |
Total number of polymer chains | 2 |
Total formula weight | 57323.65 |
Authors | Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2011-06-15, release date: 2012-12-19, Last modification date: 2023-09-13) |
Primary citation | Zhu, W.,Zhang, Y.,Sinko, W.,Hensler, M.E.,Olson, J.,Molohon, K.J.,Lindert, S.,Cao, R.,Li, K.,Wang, K.,Wang, Y.,Liu, Y.L.,Sankovsky, A.,de Oliveira, C.A.,Mitchell, D.A.,Nizet, V.,McCammon, J.A.,Oldfield, E. Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110:123-128, 2013 Cited by PubMed: 23248302DOI: 10.1073/pnas.1219899110 PDB entries with the same primary citation |
Experimental method |
Structure validation
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