6Z3T

Structure of canine Sec61 inhibited by mycolactone

Summary for 6Z3T

• Entry DOI: 10.2210/pdb6z3t/pdb
• EMDB information: 11064
• Descriptor: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit gamma, Protein transport protein Sec61 subunit beta, ... (4 entities in total)
• Functional Keywords: sec61; mycolactone; ribosome-translocon complex; translocation inhibitor, membrane protein
• Biological source: Canis lupus familiaris (Dog); More
• Total number of polymer chains: 3
• Total formula weight: 62494.84

Authors

Gerard, S.F.,Higgins, M.K. (deposition date: 2020-05-21, release date: 2020-07-22, Last modification date: 2020-08-19)

• Primary citation: Gerard, S.F.,Hall, B.S.,Zaki, A.M.,Corfield, K.A.,Mayerhofer, P.U.,Costa, C.,Whelligan, D.K.,Biggin, P.C.,Simmonds, R.E.,Higgins, M.K.; Structure of the Inhibited State of the Sec Translocon.; Mol.Cell, 79:406-415.e7, 2020; PubMed: 32692975; DOI: 10.1016/j.molcel.2020.06.013

Experimental method

ELECTRON MICROSCOPY (2.69 Å)