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6Z3T

Structure of canine Sec61 inhibited by mycolactone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein transport protein Sec61 subunit alpha isoform 1polymer47652279.41UniProt (P38377)
Pfam (PF10559)
Pfam (PF00344)
Canis lupus familiaris (Dog)Sec61 alpha-1
2B
(B)
Protein transport protein Sec61 subunit gammapolymer687752.31UniProt (P60058)
Pfam (PF00584)
Canis lupus familiaris (Dog)
3C
(C)
Protein transport protein Sec61 subunit betapolymer201720.11Canis lupus familiaris (Dog)
4D
(A)
[(6~{S},7~{S},9~{Z},12~{R})-12-[(~{Z},2~{S},6~{R},7~{R},9~{R})-4,6-dimethyl-7,9-bis(oxidanyl)dec-4-en-2-yl]-7,9-dimethyl-2-oxidanylidene-1-oxacyclododec-9-en-6-yl] (2~{E},4~{E},6~{E},8~{E},10~{E},12~{S},13~{S},15~{S})-4,6,10-trimethyl-12,13,15-tris(oxidanyl)hexadeca-2,4,6,8,10-pentaenoatenon-polymer743.01Chemie (Q6B)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight61751.8
Non-Polymers*Number of molecules1
Total formula weight743.0
All*Total formula weight62494.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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