5D5M

Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR

Summary for 5D5M
DescriptorMajor histocompatibility complex class I-related gene protein, Beta-2-microglobulin, M33.64 TCR Alpha Chain, ... (8 entities in total)
Functional Keywordsantigen, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationCell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted. Isoform 3: Cell membrane ; Single-pass type I membrane protein : Q95460
Secreted : P61769
Total number of polymer chains8
Total formula weight188260.19
Authors
Keller, A.N.,Birkinshaw, R.W.,Rossjohn, J. (deposition date: 2015-08-11, release date: 2016-01-27, Last modification date: 2016-02-03)
Primary citationBirkinshaw, R.W.,Eckle, S.B.,Fairlie, D.P.,Gherardin, N.A.,Godfrey, D.I.,Keller, A.N.,Le Nours, J.,Liu, L.,McCluskey, J.,Neeson, P.J.,Pellicci, D.G.,Ritchie, D.S.,Rossjohn, J.,Uldrich, A.P.,Waddington, J.N.,Woolley, R.E.
Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44:32-45, 2016
PubMed: 26795251
DOI: 110.1016/j.immuni.2015.12.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
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PDB entries from 2021-06-23