2YXJ
| Crystal structure of Bcl-xL in complex with ABT-737 | 分子名称: | 4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE, Apoptosis regulator Bcl-X, CHLORIDE ION, ... | 著者 | Czabotar, P.E, Lee, E.F, Smith, B.J, Deshayes, K, Zobel, K, Fairlie, W.D, Colman, P.M. | 登録日 | 2007-04-26 | 公開日 | 2007-05-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family Cell Death Differ., 14, 2007
|
|
4G8E
| Crystal Structure of clone18 TCR | 分子名称: | alpha chain clone 18 TCR, beta chain clone 18 TCR | 著者 | Gras, S, Bhati, M, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat.Immunol., 14, 2013
|
|
4G8F
| Crystal Structure of clone42 TCR | 分子名称: | alpha chain clone 42 TCR, beta chain clone 42 TCR | 著者 | Gras, S, Bhati, M, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat.Immunol., 14, 2013
|
|
4JK5
| Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Ser) | 分子名称: | 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | 著者 | Buth, S.A, Leiman, P.G, Chen, S, Heinis, C. | 登録日 | 2013-03-09 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids. Chembiochem, 14, 2013
|
|
3CFX
| Crystal structure of M. acetivorans periplasmic binding protein ModA/WtpA with bound tungstate | 分子名称: | GLYCEROL, MAGNESIUM ION, TUNGSTATE(VI)ION, ... | 著者 | Comellas-Bigler, M, Hollenstein, K, Locher, K.P. | 登録日 | 2008-03-04 | 公開日 | 2009-03-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins. J.Biol.Inorg.Chem., 14, 2009
|
|
5CHH
| Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | 分子名称: | AraC family transcriptional regulator | 著者 | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | 登録日 | 2015-07-10 | 公開日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa Plos Biol., 14, 2016
|
|
3CG3
| |
5TY4
| MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution | 分子名称: | TGF-beta receptor type-2, mmTGF-b2-7m | 著者 | Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T. | 登録日 | 2016-11-18 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.9 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
4JK6
| Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Aba) | 分子名称: | 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | 著者 | Buth, S.A, Leiman, P.G, Chen, S, Heinis, C. | 登録日 | 2013-03-09 | 公開日 | 2013-07-17 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids. Chembiochem, 14, 2013
|
|
5U8K
| RitR mutant - C128S | 分子名称: | Response regulator | 著者 | Silvaggi, N.R, Han, L. | 登録日 | 2016-12-14 | 公開日 | 2017-12-20 | 最終更新日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization. PLoS Pathog., 14, 2018
|
|
3C52
| Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with phosphoglycolohydroxamic acid, a competitive inhibitor | 分子名称: | CALCIUM ION, Fructose-bisphosphate aldolase, PHOSPHOGLYCOLOHYDROXAMIC ACID, ... | 著者 | Coincon, M, Sygusch, J. | 登録日 | 2008-01-30 | 公開日 | 2008-08-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics. Chemistry, 14, 2008
|
|
4K8X
| Binary complex of 9N DNA polymerase in the replicative state | 分子名称: | 1,2-ETHANEDIOL, 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, CHLORIDE ION, ... | 著者 | Betz, K, Diederichs, K, Marx, A. | 登録日 | 2013-04-19 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex Chembiochem, 14, 2013
|
|
5CUO
| |
5CUP
| |
5D21
| Multivalency Effects in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting Lectin LecA | 分子名称: | CALCIUM ION, LecA, phenyl beta-D-galactopyranoside | 著者 | Bergmann, M, Michaud, G, Visini, R, Jin, X, Stocker, A, Darbre, T, Reymond, J.-L. | 登録日 | 2015-08-05 | 公開日 | 2015-11-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Multivalency effects on Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. Org.Biomol.Chem., 14, 2016
|
|
5U8M
| |
4JCK
| |
4JGX
| The Structure of Sterol Carrier Protein 2 from the Yeast Yarrowia Lipolytica | 分子名称: | CITRIC ACID, Fatty acid-binding protein, PALMITIC ACID | 著者 | De Berti, F.P, Capaldi, S, Acierno, J.P, Klinke, S, Monaco, H.L, Ermacora, M.R. | 登録日 | 2013-03-04 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of sterol carrier protein 2 from Yarrowia lipolytica and the evolutionary conservation of a large, non-specific lipid-binding cavity. J.Struct.Funct.Genom., 14, 2013
|
|
5TFX
| |
4JC1
| |
2Z5L
| |
4JIP
| |
5UPQ
| Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP465 ligand | 分子名称: | 5'-O-[(R)-{[(7beta,8alpha,9beta,10alpha,13alpha,16beta)-7,16-dihydroxy-18-oxokauran-18-yl]oxy}(hydroxy)phosphoryl]adenosine, Acyl-CoA synthetase PtmA2, CHLORIDE ION, ... | 著者 | Osipiuk, J, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J.D, Chang, C.Y, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-02-03 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14, 2018
|
|
3CG1
| |
5V8D
| Structure of Bacillus cereus PatB1 with sulfonyl adduct | 分子名称: | Bacillus cereus PatB1, SULFATE ION | 著者 | Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J. | 登録日 | 2017-03-21 | 公開日 | 2017-10-18 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides. Nat. Chem. Biol., 14, 2018
|
|