5U8M
A novel family of redox sensors in the streptococci evolved from two-component response regulators
Summary for 5U8M
Entry DOI | 10.2210/pdb5u8m/pdb |
Related | 5U8K |
Descriptor | Response regulator (2 entities in total) |
Functional Keywords | repressor of iron transporter, aspartate-less receiver domain protein, transcription regulator, cross-dimer, transcription |
Biological source | Streptococcus pneumoniae (strain Hungary19A-6) |
Total number of polymer chains | 2 |
Total formula weight | 54064.64 |
Authors | Han, L.,Silvaggi, N.R. (deposition date: 2016-12-14, release date: 2017-12-20, Last modification date: 2023-10-04) |
Primary citation | Glanville, D.G.,Han, L.,Maule, A.F.,Woodacre, A.,Thanki, D.,Abdullah, I.T.,Morrissey, J.A.,Clarke, T.B.,Yesilkaya, H.,Silvaggi, N.R.,Ulijasz, A.T. RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization. PLoS Pathog., 14:e1007052-e1007052, 2018 Cited by PubMed: 29750817DOI: 10.1371/journal.ppat.1007052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.105 Å) |
Structure validation
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