2Z5L
The first ketoreductase of the tylosin PKS
Summary for 2Z5L
| Entry DOI | 10.2210/pdb2z5l/pdb |
| Descriptor | Tylactone synthase starter module and modules 1 & 2 (2 entities in total) |
| Functional Keywords | short-chain dehydrogenase/reductase, rossmann fold, polyketide synthase ketoreductase, transferase |
| Biological source | Streptomyces fradiae |
| Total number of polymer chains | 1 |
| Total formula weight | 53306.01 |
| Authors | Keatinge-Clay, A.T.,Stroud, R.M. (deposition date: 2007-07-14, release date: 2007-08-28, Last modification date: 2023-11-01) |
| Primary citation | Keatinge-Clay, A.T. A tylosin ketoreductase reveals how chirality is determined in polyketides Chem.Biol., 14:898-908, 2007 Cited by PubMed: 17719489DOI: 10.1016/j.chembiol.2007.07.009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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