5UPQ
Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP465 ligand
Summary for 5UPQ
Entry DOI | 10.2210/pdb5upq/pdb |
Related | 5E7Q 5UPS 5UPT |
Descriptor | Acyl-CoA synthetase PtmA2, 5'-O-[(R)-{[(7beta,8alpha,9beta,10alpha,13alpha,16beta)-7,16-dihydroxy-18-oxokauran-18-yl]oxy}(hydroxy)phosphoryl]adenosine, SULFATE ION, ... (6 entities in total) |
Functional Keywords | acyl-coa synthetase, ptma2, structural genomics, apc109894, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, psi-biology, transferase |
Biological source | Streptomyces platensis subsp. rosaceus |
Total number of polymer chains | 2 |
Total formula weight | 117714.23 |
Authors | Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Babnigg, G.,Rudolf, J.D.,Chang, C.Y.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2017-02-03, release date: 2017-02-22, Last modification date: 2023-11-15) |
Primary citation | Wang, N.,Rudolf, J.D.,Dong, L.B.,Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Chang, C.Y.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B. Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14:730-737, 2018 Cited by PubMed: 29867143DOI: 10.1038/s41589-018-0061-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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