PDB: 31489 件ウェブページステータス検索Chemie searchBIRD

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8AVT	Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of glycerol 3-phosphate 分子名称: 1,2-ETHANEDIOL, Bacteriocin aureocin A53, D-Aureocin A53, ... 著者 Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. 登録日 2022-08-26 公開日 2023-07-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
8TSB	Human PI3K p85alpha/p110alpha bound to compound 2 分子名称: 5-(3-bromo-5-fluorobenzamido)-N-methyl-6-(2-methylanilino)pyridine-3-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Holliday, M, Tang, Y, Bulku, A, Wilbur, J, Fraser, J. 登録日 2023-08-11 公開日 2023-11-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.53 Å) 主引用文献 Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3K alpha Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discov, 14, 2024
7REH	Crystal structure of T252E CYP199A4 bound to 4-methoxybenzoic acid 分子名称: 4-METHOXYBENZOIC ACID, ACETATE ION, CHLORIDE ION, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2021-07-12 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.545 Å) 主引用文献 An Altered Heme Environment in an Engineered Cytochrome P450 Enzyme Enables the Switch from Monooxygenase to Peroxygenase Activity Acs Catalysis, 2022
8AX8	Human Apolipoprotein E4 (ApoE4) N-terminal domain (space group P3121) 分子名称: Maltose/maltodextrin-binding periplasmic protein,Apolipoprotein E 著者 Nemergut, M, Marek, M. 登録日 2022-08-31 公開日 2023-08-02 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Mol Neurodegener, 18, 2023
8TRS	Structure of the EphA2 CRD bound to FabS1CE_C1, trigonal form 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. 登録日 2023-08-10 公開日 2023-11-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
7RLZ	Antibody 2F2 in complex with P. vivax CSP peptide GDRAAGQPAGNGAGGQAA 分子名称: 2F2 Fab heavy chain, 2F2 Fab light chain, peptide from Circumsporozoite protein variant VK210 著者 Kucharska, I, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
7RM1	Antibody 2F2 in complex with P. vivax CSP peptide EDGAGNQPGANGAGNQPGANGAGNQPG 分子名称: 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247 著者 Kucharska, I, Ivanochko, D, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
7MWM	Crystal structure of MBD2 with DNA 分子名称: DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION 著者 Liu, K, Dong, A, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) 登録日 2021-05-17 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Crystal structure of MBD2 with DNA To Be Published
8AVR	Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of sulfate 分子名称: 1,2-ETHANEDIOL, Bacteriocin aureocin A53, D-Aureocin A53, ... 著者 Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. 登録日 2022-08-26 公開日 2023-07-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
7B4Y	Structure of the M298L mutant of the Streptomyces coelicolor small laccase T1 copper axial ligand 分子名称: COPPER (II) ION, Putative copper oxidase 著者 Zovo, K, Majumdar, S, Lukk, T. 登録日 2020-12-02 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2). Acs Omega, 7, 2022
6HLK	Hijacking the Hijackers: Escherichia coli Pathogenicity Islands Redirect Helper Phage Packaging for Their Own Benefit. 分子名称: Redirecting phage packaging protein C (RppC) 著者 Penades, J.R, Bacarizo, J, Marina, A, Alqasmi, M, Fillol-Salom, A, Roszak, A.W, Ciges-Tomas, J.R. 登録日 2018-09-11 公開日 2019-07-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Hijacking the Hijackers: Escherichia coli Pathogenicity Islands Redirect Helper Phage Packaging for Their Own Benefit. Mol.Cell, 75, 2019
7RLX	Antibody 2F2 in complex with P. vivax CSP peptide GDRADGQPAGDRAAGQPA 分子名称: 2F2 Fab heavy chain, 2F2 Fab light chain, peptide from Circumsporozoite protein variant VK210 著者 Kucharska, I, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
8T8I	Structure of VHH-Fab complex with engineered Elbow FNQIKG, Crystal Kappa and SER substitutions 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab heavy chain, ... 著者 Filippova, E.V, Thompson, I, Kossiakoff, A.A. 登録日 2023-06-22 公開日 2023-11-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
7RLY	Antibody 2F2 in complex with P. vivax CSP peptide DRAAGQPAGDRADGQPA 分子名称: 2F2 Fab heavy chain, 2F2 Fab light chain, peptide from Circumsporozoite protein variant VK210 著者 Kucharska, I, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
8THS	Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, LEA A69T 分子名称: DI(HYDROXYETHYL)ETHER, KAEDE-TYPE RED FLUORESCENT PROTEIN, LEA A69T, ... 著者 Henderson, J.N, Mills, J.H. 登録日 2023-07-17 公開日 2023-11-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Capturing excited-state structural snapshots of evolutionary green-to-red photochromic fluorescent proteins. Front Chem, 11, 2023
6HX9	Putrescine transaminase from Pseudomonas putida 分子名称: Aspartate aminotransferase family protein 著者 Gahloth, D. 登録日 2018-10-16 公開日 2019-06-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Characterization of a Putrescine Transaminase FromPseudomonas putidaand its Application to the Synthesis of Benzylamine Derivatives. Front Bioeng Biotechnol, 6, 2018
7RLV	Antibody 2F2 in complex with P. vivax CSP peptide GDRADGQPAGDRADGQPA 分子名称: 1,2-ETHANEDIOL, 2F2 Fab heavy chain, 2F2 Fab light chain, ... 著者 Kucharska, I, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
8AVS	Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of citrate and acetate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Bacteriocin aureocin A53, ... 著者 Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. 登録日 2022-08-26 公開日 2023-07-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
6HXH	Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
7RM0	Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG 分子名称: 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247 著者 Kucharska, I, Ivanochko, D, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
8T7F	Structure of the S1 variant of Fab F1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ... 著者 Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. 登録日 2023-06-20 公開日 2023-11-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
6HZF	BP0997, GH138 enzyme targeting pectin rhamnogalacturonan II 分子名称: BPa0997, SERINE, SODIUM ION 著者 Basle, A, Cartmell, A, Labourel, A, Gilbert, H. 登録日 2018-10-23 公開日 2019-03-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and functional analyses of glycoside hydrolase 138 enzymes targeting chain A galacturonic acid in the complex pectin rhamnogalacturonan II. J.Biol.Chem., 294, 2019
7RLW	Antibody 2F2 in complex with P. vivax CSP peptide GDRAAGQPAGDRAAGQPA 分子名称: 2F2 Fab heavy chain, 2F2 Fab light chain, PvCSPvk210 peptide from Circumsporozoite protein 著者 Kucharska, I, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022
8TN2	Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxal-5'-phosphate (PLP) 分子名称: PLP-dependent aminotransferase MppQ 著者 Silvaggi, N.R, Vuksanovic, N. 登録日 2023-08-01 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus. Biochemistry, 62, 2023
7RM3	Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPGANGAGGQAA 分子名称: 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, ACETATE ION, ... 著者 Kucharska, I, Ivanochko, D, Julien, J.P. 登録日 2021-07-26 公開日 2022-01-26 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11, 2022

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