7RLX

Antibody 2F2 in complex with P. vivax CSP peptide GDRADGQPAGDRAAGQPA

Summary for 7RLX

Entry DOI	10.2210/pdb7rlx/pdb
Descriptor	2F2 Fab light chain, 2F2 Fab heavy chain, peptide from Circumsporozoite protein variant VK210, ... (4 entities in total)
Functional Keywords	antibody, malaria, plasmodium vivax, circumsporozoite protein, antimicrobial protein
Biological source	Mus musculus (mouse) More
Total number of polymer chains	3
Total formula weight	50042.70
Authors	Kucharska, I.,Julien, J.P. (deposition date: 2021-07-26, release date: 2022-01-26, Last modification date: 2023-10-18)
Primary citation	Kucharska, I.,Hossain, L.,Ivanochko, D.,Yang, Q.,Rubinstein, J.L.,Pomes, R.,Julien, J.P. Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11:-, 2022 Cited by PubMed: 35023832 DOI: 10.7554/eLife.72908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation