7RM1
Antibody 2F2 in complex with P. vivax CSP peptide EDGAGNQPGANGAGNQPGANGAGNQPG
Summary for 7RM1
| Entry DOI | 10.2210/pdb7rm1/pdb |
| Descriptor | 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247 (3 entities in total) |
| Functional Keywords | antibody, malaria, plasmodium vivax, circumsporozoite protein, antimicrobial protein |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 5 |
| Total formula weight | 98688.87 |
| Authors | Kucharska, I.,Ivanochko, D.,Julien, J.P. (deposition date: 2021-07-26, release date: 2022-01-26, Last modification date: 2023-10-18) |
| Primary citation | Kucharska, I.,Hossain, L.,Ivanochko, D.,Yang, Q.,Rubinstein, J.L.,Pomes, R.,Julien, J.P. Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11:-, 2022 Cited by PubMed: 35023832DOI: 10.7554/eLife.72908 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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