PDB: 2917 件ウェブページステータス検索Chemie searchBIRD

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5VGD	Crystal Structure of HLA-C*0501 in complex with SAE 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-5 alpha chain, ... 著者 Gras, S, Rossjohn, J. 登録日 2017-04-11 公開日 2017-05-31 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural and regulatory diversity shape HLA-C protein expression levels. Nat Commun, 8, 2017
5VVP	HLA-B*57:03 presenting LSSPVTKSW 分子名称: Beta-2-microglobulin, LEU-SER-SER-PRO-VAL-THR-LYS-SER-TRP, MHC class I antigen 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-19 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
1HSA	THE THREE-DIMENSIONAL STRUCTURE OF HLA-B27 AT 2.1 ANGSTROMS RESOLUTION SUGGESTS A GENERAL MECHANISM FOR TIGHT PEPTIDE BINDING TO MHC 分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-B*2705), MODEL PEPTIDE SEQUENCE - ARAAAAAAA 著者 Madden, D.R, Gorga, J.C, Strominger, J.L, Wiley, D.C. 登録日 1992-08-11 公開日 1992-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC. Cell(Cambridge,Mass.), 70, 1992
5W1V	Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex 分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... 著者 Gras, S, Walpole, N, Farenc, C, Rossjohn, J. 登録日 2017-06-04 公開日 2017-10-04 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
5W42	Crystal structure of human monoclonal antibody H3v-47 in complex with influenza virus hemagglutinin from A/Minnesota/11/2010 (H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H3v-47 heavy chain, ... 著者 Zhang, H, Wilson, I.A. 登録日 2017-06-08 公開日 2018-07-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.569 Å) 主引用文献 A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
1HLA	STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2 分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) (ALPHA CHAIN) 著者 Bjorkman, P.J, Saper, M.A, Samraoui, B, Bennett, W.S, Strominger, J.L, Wiley, D.C. 登録日 1987-10-15 公開日 1988-01-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of the human class I histocompatibility antigen, HLA-A2. Nature, 329, 1987
5VJ6	BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 分子名称: 8ANC195 Fab heavy chain, 8ANC195 Fab light chain, Envelope glycoprotein gp160, ... 著者 Wang, H, Bjorkman, P.J. 登録日 2017-04-18 公開日 2017-06-21 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (11.5 Å) 主引用文献 Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. Elife, 6, 2017
5VOB	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
5VEB	Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Cadherin-6, anti-CDH6 Fab heavy chain, ... 著者 Zhu, X, Bialucha, C.U, London, A, Clark, K, Hu, T. 登録日 2017-04-04 公開日 2017-06-07 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers. Cancer Discov, 7, 2017
5VIG	Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII 分子名称: CITRATE ANION, Fab heavy chain, Fab light chain, ... 著者 Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. 登録日 2017-04-16 公開日 2017-05-03 最終更新日 2017-05-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
1HYR	CRYSTAL STRUCTURE OF HUMAN MICA IN COMPLEX WITH NATURAL KILLER CELL RECEPTOR NKG2D 分子名称: MHC CLASS I CHAIN-RELATED PROTEIN A, NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN 著者 Li, P, Strong, R.K. 登録日 2001-01-21 公開日 2001-05-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nat.Immunol., 2, 2001
1HQR	CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II 分子名称: HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... 著者 Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. 登録日 2000-12-19 公開日 2001-01-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II. Immunity, 14, 2001
5V4M	Structure of HLA-DR15 with bound alpha3(135-145) peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ... 著者 Petersen, J, Rossjohn, J. 登録日 2017-03-10 公開日 2017-05-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature, 545, 2017
5W1M	MACV GP1 CR1-07 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... 著者 Raymond, D.D, Clark, L.E, Abraham, J. 登録日 2017-06-03 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.91 Å) 主引用文献 Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
5VWF	HLA-B*58:03 presenting LTVQVARVY 分子名称: Beta-2-microglobulin, MHC class I antigen, Nonamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TYR 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-21 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
5VUD	HLA-B*57:01 presenting LSSPVTKSW 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-19 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
5VPL	CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C1 - HEAVY CHAIN, ... 著者 Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. 登録日 2017-05-05 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens. J.Biol.Chem., 287, 2012
5W6A	HLA-C*06:02 presenting ARTELYRSL 分子名称: ALA-ARG-THR-GLU-LEU-TYR-ARG-SER-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Mobbs, J.I, Vivian, J.P, Rossjohn, J. 登録日 2017-06-16 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule. J. Biol. Chem., 292, 2017
5W6G	Human antibody 6649 in complex with influenza hemagglutinin H1 Solomon Islands 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6649 antibody heavy chain, ... 著者 Raymond, D.D, Harrison, S.C. 登録日 2017-06-16 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VL7	PCSK9 complex with Fab33 分子名称: Fab33 heavy chain, Fab33 light chain, Proprotein convertase subtilisin/kexin type 9 著者 Eigenbrot, C, Shia, S. 登録日 2017-04-25 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Nat. Struct. Mol. Biol., 24, 2017
5VOC	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 - Low resolution dataset for initial phasing by SAD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.99 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
5VZY	Crystal structure of crenezumab Fab in complex with Abeta 分子名称: Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain 著者 Ultsch, M, Wang, W. 登録日 2017-05-29 公開日 2017-08-09 最終更新日 2017-09-13 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin. Sci Rep, 6, 2016
5W08	A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 McCarthy, K.R, Harrison, S.C. 登録日 2017-05-30 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity, 48, 2018
3EJZ	Structure of E203V mutant E.coli Cl-/H+ exchanger, CLC-ec1 分子名称: BROMIDE ION, Fab fragment, Heavy chain, ... 著者 Lim, H.-H, Miller, C. 登録日 2008-09-18 公開日 2009-02-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger. J.Gen.Physiol., 133, 2009
3E6F	MHC CLASS I H-2Dd Heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PA9, from the Human immunodeficiency virus (BaL) envelope glycoprotein 120 分子名称: BETA-2 MICROGLOBULIN, Envelope glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ... 著者 Wang, R, Natarajan, K, Robinson, H, Margulies, D.H. 登録日 2008-08-15 公開日 2009-08-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity J.Immunol., 183, 2009

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