PDB: 2759 件ウェブページステータス検索Chemie searchBIRD

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1CP3	CRYSTAL STRUCTURE OF THE COMPLEX OF APOPAIN WITH THE TETRAPEPTIDE INHIBITOR ACE-DVAD-FMC 分子名称: ACETYL-ASP-VAL-ALA-ASP-FLUOROMETHYLKETONE, APOPAIN 著者 Mittl, P.R.E, Dimarco, S, Gruetter, M.G. 登録日 1996-12-12 公開日 1997-12-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone. J.Biol.Chem., 272, 1997
8FEG	CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1 分子名称: ACE-TYR-ALA-DTY-THR-THR-CYS-THR-DPN-XT9, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Fay, J.F, Che, T. 登録日 2022-12-06 公開日 2023-12-06 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nat Commun, 14, 2023
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Pena, V. 登録日 2022-01-15 公開日 2023-05-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
7RJ8	CRYSTAL STRUCTURE OF AP2 ASSOCIATED KINASE 1 ISOFORM 1 COMPLEXED WITH LIGAND (2R)-2-AMINO-N-[3-(DIFLUOROM ETHOXY)-4-(1,3-OXAZOL-5-YL)PHENYL]-4-METHYLPENTANAMIDE 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5-[(4-aminopiperidin-1-yl)methyl]-N-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine, AP2-associated protein kinase 1, ... 著者 Pokross, M, Muckelbauer, J. 登録日 2021-07-20 公開日 2022-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors. J.Med.Chem., 65, 2022
7RJ6	CRYSTAL STRUCTURE OF AP2 ASSOCIATED KINASE 1 ISOFORM 1 COMPLEXED WITH LIGAND (2R)-2-AMINO-N-[3-(DIFLUOROM ETHOXY)-4-(1,3-OXAZOL-5-YL)PHENYL]-4-METHYLPENTANAMIDE 分子名称: (1S)-1-[4-ethyl-6-(1,3-oxazol-5-yl)quinazolin-2-yl]-3-methylbutan-1-amine, 5-[(4-aminopiperidin-1-yl)methyl]-N-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine, AP2-associated protein kinase 1, ... 著者 Muckelbauer, J. 登録日 2021-07-20 公開日 2022-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.132 Å) 主引用文献 Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors. J.Med.Chem., 65, 2022
7RJ7	CRYSTAL STRUCTURE OF AP2 ASSOCIATED KINASE 1 ISOFORM 1 COMPLEXED WITH LIGAND 2-(1-AMINO-3-METHYLBUTYL)-6- (PYRIDIN-4-YL)QUINOLINE-4-CARBONITRILE 分子名称: 2-[(1S)-1-amino-3-methylbutyl]-6-(pyridin-4-yl)quinoline-4-carbonitrile, AP2-associated protein kinase 1, SULFATE ION 著者 Muckelbauer, J. 登録日 2021-07-20 公開日 2022-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.124 Å) 主引用文献 Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors. J.Med.Chem., 65, 2022
1DMT	STRUCTURE OF HUMAN NEUTRAL ENDOPEPTIDASE COMPLEXED WITH PHOSPHORAMIDON 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... 著者 Oefner, C, D'Arcy, A, Hennig, M, Winkler, F.K, Dale, G.E. 登録日 1999-12-15 公開日 2000-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon. J.Mol.Biol., 296, 2000
1DX5	Crystal structure of the thrombin-thrombomodulin complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ... 著者 Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W. 登録日 1999-12-20 公開日 2000-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex Nature, 404, 2000
8GU0	Crystal structure of a fungal halogenase RadH 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Non-heme halogenase radH, ... 著者 Jiang, S.M, Brown, C.J. 登録日 2022-09-09 公開日 2023-07-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Further Characterization of Fungal Halogenase RadH and Its Homologs. Biomolecules, 13, 2023
8GW0	Crystal structure of the human dihydroorotase domain in complex with malic acid 分子名称: (2S)-2-hydroxybutanedioic acid, CAD protein, ZINC ION 著者 Yang, P.C, Liu, H.W, Huang, H.Y, Huang, C.Y. 登録日 2022-09-16 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13, 2023
8GVZ	Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil 分子名称: 5-FLUOROURACIL, CAD protein, ZINC ION 著者 Liu, H.W, Yang, P.C, Huang, H.Y, Huang, C.Y. 登録日 2022-09-16 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13, 2023
2ZVR	Crystal structure of a D-tagatose 3-epimerase-related protein from Thermotoga maritima 分子名称: Uncharacterized protein TM_0416 著者 Sakuraba, H, Ohshima, T. 登録日 2008-11-14 公開日 2009-03-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a D-tagatose 3-epimerase-related protein from the hyperthermophilic bacterium Thermotoga maritima Acta Crystallogr.,Sect.F, 65, 2009
2CG9	Crystal structure of an Hsp90-Sba1 closed chaperone complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, CO-CHAPERONE PROTEIN SBA1 著者 Ali, M.M.U, Roe, S.M, Prodromou, C, Pearl, L.H. 登録日 2006-03-01 公開日 2006-04-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of an Hsp90-Nucleotide-P23/Sba1 Closed Chaperone Complex Nature, 440, 2006
2CGE	Crystal structure of an Hsp90-Sba1 closed chaperone complex 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Ali, M.M.U, Roe, S.M, Prodromou, C, Pearl, L.H. 登録日 2006-03-01 公開日 2006-04-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of an Hsp90-Nucleotide-P23/Sba1 Closed Chaperone Complex Nature, 440, 2006
8HS2	Orphan GPR20 in complex with Fab046 分子名称: Light chain of Fab046, Soluble cytochrome b562,G-protein coupled receptor 20, heavy chain of Fab046 著者 Lin, X, Jiang, S, Xu, F. 登録日 2022-12-16 公開日 2023-03-08 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 The activation mechanism and antibody binding mode for orphan GPR20. Cell Discov, 9, 2023
2FSA	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state 分子名称: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor 著者 Li, H, Patel, D.J. 登録日 2006-01-21 公開日 2006-07-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
2FUI	NMR solution structure of PHD finger fragment of human BPTF in free state 分子名称: bromodomain PHD finger transcription factor 著者 Ilin, S, Patel, D.J. 登録日 2006-01-26 公開日 2006-07-11 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
2FUU	NMR solution structure of the PHD domain from the human BPTF in complex with H3(1-15)K4me3 peptide 分子名称: Histone H3, ZINC ION, bromodomain PHD finger transcription factor 著者 Ilin, S, Patel, D.J. 登録日 2006-01-27 公開日 2006-07-11 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
2F6J	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state 分子名称: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ... 著者 Li, H, Patel, D.J. 登録日 2005-11-29 公開日 2006-07-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
2FV5	Crystal structure of TACE in complex with IK682 分子名称: (2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE, ADAM 17, ZINC ION 著者 Orth, P, Niu, X. 登録日 2006-01-30 公開日 2006-07-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 IK682, a tight binding inhibitor of TACE. Arch.Biochem.Biophys., 451, 2006
2F6N	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the free form 分子名称: ZINC ION, bromodomain PHD finger transcription factor 著者 Li, H, Patel, D.J. 登録日 2005-11-29 公開日 2006-07-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Schmitzova, J, Pena, V. 登録日 2023-02-07 公開日 2023-05-10 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
4FZ0	Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at low pH 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHLORIDE ION, ... 著者 Baconguis, I, Gouaux, E. 登録日 2012-07-05 公開日 2012-08-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes. Nature, 489, 2012
5I9T	Caspase 3 V266C 分子名称: ACE-ASP-GLU-VAL-ASK, ACETATE ION, Caspase-3 著者 Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. 登録日 2016-02-20 公開日 2016-10-26 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
8C6J	Human spliceosomal PM5 C* complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Dybkov, O, Kastner, B, Luehrmann, R. 登録日 2023-01-12 公開日 2023-07-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023

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