8GVZ

Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil

Summary for 8GVZ

Entry DOI	10.2210/pdb8gvz/pdb
Descriptor	CAD protein, 5-FLUOROURACIL, ZINC ION, ... (4 entities in total)
Functional Keywords	dihydroorotase, human cad, hydrolase, zn
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43022.74
Authors	Liu, H.W.,Yang, P.C.,Huang, H.Y.,Huang, C.Y. (deposition date: 2022-09-16, release date: 2023-09-20, Last modification date: 2023-11-15)
Primary citation	Lin, E.S.,Huang, Y.H.,Yang, P.C.,Peng, W.F.,Huang, C.Y. Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13:-, 2023 Cited by PubMed: 36671534 DOI: 10.3390/biom13010149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation