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8GVZ

Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil

Summary for 8GVZ
Entry DOI10.2210/pdb8gvz/pdb
DescriptorCAD protein, 5-FLUOROURACIL, ZINC ION, ... (4 entities in total)
Functional Keywordsdihydroorotase, human cad, hydrolase, zn
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight43022.74
Authors
Liu, H.W.,Yang, P.C.,Huang, H.Y.,Huang, C.Y. (deposition date: 2022-09-16, release date: 2023-09-20, Last modification date: 2023-11-15)
Primary citationLin, E.S.,Huang, Y.H.,Yang, P.C.,Peng, W.F.,Huang, C.Y.
Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13:-, 2023
Cited by
PubMed: 36671534
DOI: 10.3390/biom13010149
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

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