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8GVZ

Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CAD proteinpolymer39142761.81UniProt (P27708)
Pfam (PF01979)
Homo sapiens (human)
2B
(A)
5-FLUOROURACILnon-polymer130.11Chemie (URF)
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
4E
(A)
waterwater18.0260Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42761.8
Non-Polymers*Number of molecules3
Total formula weight260.9
All*Total formula weight43022.7
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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