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7DCQ
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BU of 7dcq by Molmil
cryo-EM structure of the DEAH-box helicase Prp2
分子名称: PRP2 isoform 1
著者Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y.
登録日2020-10-26
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
7DCP
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BU of 7dcp by Molmil
cryo-EM structure of the DEAH-box helicase Prp2 and coactivator Spp2
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PRP2 isoform 1, ...
著者Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y.
登録日2020-10-26
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
7DCO
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BU of 7dco by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom
分子名称: BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ...
著者Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y.
登録日2020-10-26
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
7D63
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BU of 7d63 by Molmil
Cryo-EM structure of 90S preribosome with inactive Utp24 (state C)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-29
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Cryo-EM structure of 90S preribosome with inactive Utp24 (state C)
To Be Published
7D5T
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BU of 7d5t by Molmil
Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-28
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
To Be Published
7D4I
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BU of 7d4i by Molmil
Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-24
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1
To Be Published
7BDL
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BU of 7bdl by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ADP
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
7BDK
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BU of 7bdk by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
7BDJ
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BU of 7bdj by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS
分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
7BDI
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BU of 7bdi by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ATPgammaS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C.
登録日2020-12-21
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2.
J.Biol.Chem., 297, 2021
7B9V
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BU of 7b9v by Molmil
Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound
分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K.
登録日2020-12-14
公開日2021-03-10
最終更新日2021-04-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
7AUD
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BU of 7aud by Molmil
Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ...
著者Chen, X, Oliver, A.W.
登録日2020-11-02
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
7AUC
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BU of 7auc by Molmil
Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Chen, X, Oliver, A.W.
登録日2020-11-02
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
7ASK
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BU of 7ask by Molmil
43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60
著者Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y.
登録日2020-10-27
公開日2021-04-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Cell Rep, 33, 2020
7ASE
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BU of 7ase by Molmil
43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase
分子名称: 18S, 40S ribosomal protein S10, putative, ...
著者Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y.
登録日2020-10-27
公開日2021-04-14
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Cell Rep, 33, 2020
7AQO
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BU of 7aqo by Molmil
yeast THO-Sub2 complex dimer
分子名称: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-22
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
7APX
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BU of 7apx by Molmil
yeast THO-Sub2 complex
分子名称: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-20
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
7APK
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BU of 7apk by Molmil
Structure of the human THO - UAP56 complex
分子名称: Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ...
著者Hohmann, U, Puehringer, T, Plaschka, C.
登録日2020-10-17
公開日2020-12-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the human core transcription-export complex reveals a hub for multivalent interactions.
Elife, 9, 2020
7AOI
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BU of 7aoi by Molmil
Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate
分子名称: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
著者Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A.
登録日2020-10-14
公開日2020-12-02
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
7AM2
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BU of 7am2 by Molmil
Intermediate assembly of the Large subunit from Leishmania major mitochondrial ribosome
分子名称: 50S ribosomal protein L13-like protein, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ...
著者Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y.
登録日2020-10-07
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AKP
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BU of 7akp by Molmil
Crystal structure of E. coli RNA helicase HrpA-D305A
分子名称: ATP-dependent RNA helicase HrpA
著者Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C.
登録日2020-10-01
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJU
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BU of 7aju by Molmil
Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E.
登録日2020-09-29
公開日2020-12-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
7AJT
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BU of 7ajt by Molmil
Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E.
登録日2020-09-29
公開日2020-12-30
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
7ABI
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BU of 7abi by Molmil
Human pre-Bact-2 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2021-02-10
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABG
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BU of 7abg by Molmil
Human pre-Bact-1 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2020-12-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020

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