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4DS2
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BU of 4ds2 by Molmil
Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
分子名称: Ubiquitin-conjugating enzyme E2, putative
著者Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2012-02-17
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
To be Published
3RPG
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BU of 3rpg by Molmil
Bmi1/Ring1b-UbcH5c complex structure
分子名称: E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ...
著者Bentley, M.L, Dong, K.C, Cochran, A.G.
登録日2011-04-26
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6485 Å)
主引用文献Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex.
Embo J., 30, 2011
7WLH
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BU of 7wlh by Molmil
The crystal structure of African swine fever virus I215L
分子名称: E2 ubiquitin-conjugating enzyme
著者Shen, Z, Liang, R, Yang, Y, Peng, G.
登録日2022-01-13
公開日2023-07-19
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The crystal structure of African swine fever virus I215L
To Be Published
5D0K
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BU of 5d0k by Molmil
Structure of UbE2D2:RNF165:Ub complex
分子名称: Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ...
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
分子名称: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
著者Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
登録日2013-06-28
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
4Y1L
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BU of 4y1l by Molmil
Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation
分子名称: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9
著者Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y.
登録日2015-02-08
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
3PTF
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BU of 3ptf by Molmil
X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1
著者Bosanac, I, Hymowitz, S.G.
登録日2010-12-02
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.
J.Mol.Biol., 408, 2011
4WZ3
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BU of 4wz3 by Molmil
Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2
分子名称: E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2
著者Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-11-18
公開日2015-01-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
3A4S
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BU of 3a4s by Molmil
The crystal structure of the SLD2:Ubc9 complex
分子名称: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
7UV8
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BU of 7uv8 by Molmil
Rad6-Bre1 Complex
分子名称: E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2
著者Shukla, P.K, Chandrasekharan, M.B.
登録日2022-04-29
公開日2023-01-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
1QCQ
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BU of 1qcq by Molmil
UBIQUITIN CONJUGATING ENZYME
分子名称: PROTEIN (UBIQUITIN CONJUGATING ENZYME)
著者Cook, W.J, Jeffrey, L.C, Xu, Y, Chau, V.
登録日1999-05-10
公開日1999-05-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4.
Biochemistry, 32, 1993
6JB6
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BU of 6jb6 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
To Be Published
6M2C
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BU of 6m2c by Molmil
Distinct mechanism of MUL1-RING domain simultaneously recruiting E2 enzyme and the substrate p53-TAD domain
分子名称: Mitochondrial ubiquitin ligase activator of NFKB 1, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
著者Lee, S.O, Ryu, K.S, Chi, S.-W.
登録日2020-02-27
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.
Febs J., 2022
4A4C
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BU of 4a4c by Molmil
Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
著者Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
登録日2011-10-08
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
7BXG
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BU of 7bxg by Molmil
MavC-UBE2N-Ub complex
分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
3FSH
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BU of 3fsh by Molmil
Crystal structure of the ubiquitin conjugating enzyme Ube2g2 bound to the G2BR domain of ubiquitin ligase gp78
分子名称: Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2
著者Tu, D, Brunger, A.T.
登録日2009-01-09
公開日2009-02-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.
Proc.Natl.Acad.Sci.USA, 106, 2009
4A4B
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BU of 4a4b by Molmil
Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
著者Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
登録日2011-10-08
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
6UMP
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BU of 6ump by Molmil
Crystal structure of MavC in complex with substrate mimic in P65 space group
分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Puvar, K, Iyer, S, Luo, Z.Q, Das, C.
登録日2019-10-10
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6S53
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BU of 6s53 by Molmil
Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ...
著者Kiss, L, Boland, A, Neuhaus, D, James, L.C.
登録日2019-06-30
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
4X57
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BU of 4x57 by Molmil
Structure of an Arabidopsis E2 / Membrane-anchored Ubiquitin-fold Protein Complex
分子名称: Membrane-anchored ubiquitin-fold protein 3, SULFATE ION, Ubiquitin-conjugating enzyme E2 8
著者Korolev, S, Koroleva, O, Lu, X, Downes, B.
登録日2014-12-04
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of an Arabidopsis E2 / Membrane-anchored Ubiquitin-fold ProteinComplex
To Be Published
5AIE
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BU of 5aie by Molmil
Not4 ring domain in complex with Ubc4
分子名称: GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION
著者Bhaskar, V, Basquin, J, Conti, E.
登録日2015-02-12
公開日2015-04-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
2NVU
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BU of 2nvu by Molmil
Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ...
著者Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A.
登録日2006-11-13
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
2XWU
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BU of 2xwu by Molmil
CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX
分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9
著者Gruenwald, M, Bono, F.
登録日2010-11-05
公開日2010-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation.
Embo J., 30, 2011
7R71
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BU of 7r71 by Molmil
Crystal Structure of the UbArk2C-UbcH5b~Ub complex
分子名称: Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ...
著者Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
登録日2021-06-24
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
1A3S
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BU of 1a3s by Molmil
HUMAN UBC9
分子名称: UBC9
著者Naismith, J.H, Giraud, M.
登録日1998-01-23
公開日1998-05-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin.
Acta Crystallogr.,Sect.D, 54, 1998

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