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1AH8
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STRUCTURE OF THE ORTHORHOMBIC FORM OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE
分子名称: GLYCEROL, HEAT SHOCK PROTEIN 90
著者Prodromou, C, Roe, S.M, Pearl, L.H.
登録日1997-04-14
公開日1997-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone.
Nat.Struct.Biol., 4, 1997
8OMO
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BU of 8omo by Molmil
DNA-unbound MutSbeta-ATP complex (bent clamp form)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
著者Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
登録日2023-03-31
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献DNA-unbound MutSbeta-ATP complex (bent clamp form)
To Be Published
8OMQ
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DNA-unbound MutSbeta-ATP complex (straight clamp form)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
著者Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
登録日2023-03-31
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献DNA-unbound MutSbeta-ATP complex (straight clamp form)
To Be Published
9BE2
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BU of 9be2 by Molmil
Structure of the E. coli nucleic associated protein, YejK
分子名称: Nucleoid-associated protein YejK
著者Schumacher, M.A.
登録日2024-04-13
公開日2024-05-15
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp.
Nucleic Acids Res., 52, 2024
7D7C
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CryoEM structure of gp55-dependent RNA polymerase-promoter open complex
分子名称: DNA (nontemplate strand), DNA (template strand), DNA-directed RNA polymerase subunit alpha, ...
著者Shi, J, Wen, A, Jin, S, Feng, Y.
登録日2020-10-03
公開日2021-01-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Transcription activation by a sliding clamp.
Nat Commun, 12, 2021
7AB8
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Crystal structure of a GDNF-GFRalpha1 complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Adams, S.E, Earl, C.P, Purkiss, A.G, McDonald, N.Q.
登録日2020-09-07
公開日2021-01-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
7AML
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RET/GDNF/GFRa1 extracellular complex Cryo-EM structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha, ...
著者Adams, S.E, Earl, C.P, Purkiss, A.G, McDonald, N.Q.
登録日2020-10-09
公開日2021-01-13
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
4J5F
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BU of 4j5f by Molmil
Crystal Structure of B. thuringiensis AiiA mutant F107W
分子名称: GLYCEROL, N-acyl homoserine lactonase, ZINC ION
著者Liu, C.F, Liu, D, Momb, J, Thomas, P.W, Lajoie, A, Petsko, G.A, Fast, W, Ringe, D.
登録日2013-02-08
公開日2013-06-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-gamma-lactonase from Bacillus thuringiensis.
Biochemistry, 52, 2013
4J5H
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Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site
分子名称: GLYCEROL, N-acyl homoserine lactonase, N-decanoyl-L-homoserine, ...
著者Liu, C.F, Liu, D, Momb, J, Thomas, P.W, Lajoie, A, Petsko, G.A, Fast, W, Ringe, D.
登録日2013-02-08
公開日2013-06-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-gamma-lactonase from Bacillus thuringiensis.
Biochemistry, 52, 2013
3TGM
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BU of 3tgm by Molmil
X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(1H-imidazol-1-yl)-4,4-diphenyl-2 butanone
分子名称: 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one, HEXANE-1,6-DIOL, Heme oxygenase 1, ...
著者Rahman, M.N, Jia, Z.
登録日2011-08-17
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition.
Plos One, 7, 2012
6VAF
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Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA
分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
6VAE
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Mono-ubiquitinated Fanconi Anemia ID complex bound to ICL DNA
分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
4I3H
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A three-gate structure of topoisomerase IV from Streptococcus pneumoniae
分子名称: DNA (5'-D(*CP*AP*AP*AP*GP*GP*CP*GP*GP*TP*AP*AP*TP*AP*CP*GP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*AP*AP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*TP*TP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*CP*GP*TP*AP*TP*TP*AP*CP*CP*GP*CP*CP*TP*TP*TP*G)-3'), MAGNESIUM ION, ...
著者Laponogov, I, Veselkov, D.A, Pan, X.-S, Crevel, I, Fisher, L.M, Sanderson, M.R.
登録日2012-11-26
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport.
Nucleic Acids Res., 41, 2013
6CIX
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BU of 6cix by Molmil
Lactam cyclised mimetic of a fragment of p21
分子名称: p21
著者Wegener, K.L.
登録日2018-02-25
公開日2018-07-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CEJ
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BU of 6cej by Molmil
Solution structure of a 14mer fragment of the p21 protein
分子名称: Cyclin-dependent kinase inhibitor 1
著者Wegener, K.L.
登録日2018-02-12
公開日2018-07-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CIV
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Lactam cyclised mimetic of a fragment of p21
分子名称: p21
著者Wegener, K.L.
登録日2018-02-25
公開日2018-07-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
4JUO
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BU of 4juo by Molmil
A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32
分子名称: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, ...
著者Laponogov, I, Veselkov, D.A, Pan, X.-S, Crevel, I, Fisher, L.M, Sanderson, M.R.
登録日2013-03-25
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.53 Å)
主引用文献Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport.
Nucleic Acids Res., 41, 2013
5I3H
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BU of 5i3h by Molmil
Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, POTASSIUM ION, Triosephosphate isomerase, ...
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
5I3F
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Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: Triosephosphate isomerase, glycosomal
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
5I3J
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Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: SODIUM ION, Triosephosphate isomerase, glycosomal
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
5I3I
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Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase, glycosomal
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
5I3K
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Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, SODIUM ION, Triosephosphate isomerase, ...
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
5I3G
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Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
分子名称: Triosephosphate isomerase, glycosomal
著者Drake, E.J, Gulick, A.M, Richard, J.P, Zhai, X, Kim, K, Reinhardt, C.J.
登録日2016-02-10
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
Biochemistry, 55, 2016
3N9K
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F229A/E292S Double Mutant of Exo-beta-1,3-glucanase from Candida albicans in Complex with Laminaritriose at 1.7 A
分子名称: CALCIUM ION, Glucan 1,3-beta-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ...
著者Nakatani, Y, Cutfield, S.M, Cutfield, J.F.
登録日2010-05-30
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance
Febs J., 277, 2010
3P2X
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Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A.
登録日2010-10-04
公開日2011-11-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published

223532

件を2024-08-07に公開中

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