3TGM
X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(1H-imidazol-1-yl)-4,4-diphenyl-2 butanone
Summary for 3TGM
Entry DOI | 10.2210/pdb3tgm/pdb |
Related | 1N45 3CZY 3HOK 3K4F |
Descriptor | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one, ... (5 entities in total) |
Functional Keywords | alpha helix, oxidoreductase, heme, microsomes, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Microsome: P09601 |
Total number of polymer chains | 2 |
Total formula weight | 55729.10 |
Authors | Rahman, M.N.,Jia, Z. (deposition date: 2011-08-17, release date: 2012-02-01, Last modification date: 2023-09-13) |
Primary citation | Rahman, M.N.,Vlahakis, J.Z.,Vukomanovic, D.,Lee, W.,Szarek, W.A.,Nakatsu, K.,Jia, Z. A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition. Plos One, 7:e29514-e29514, 2012 Cited by PubMed: 22276118DOI: 10.1371/journal.pone.0029514 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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