3TGM

X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(1H-imidazol-1-yl)-4,4-diphenyl-2 butanone

Summary for 3TGM

Entry DOI	10.2210/pdb3tgm/pdb
Related	1N45 3CZY 3HOK 3K4F
Descriptor	Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one, ... (5 entities in total)
Functional Keywords	alpha helix, oxidoreductase, heme, microsomes, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Microsome: P09601
Total number of polymer chains	2
Total formula weight	55729.10
Authors	Rahman, M.N.,Jia, Z. (deposition date: 2011-08-17, release date: 2012-02-01, Last modification date: 2023-09-13)
Primary citation	Rahman, M.N.,Vlahakis, J.Z.,Vukomanovic, D.,Lee, W.,Szarek, W.A.,Nakatsu, K.,Jia, Z. A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition. Plos One, 7:e29514-e29514, 2012 Cited by PubMed: 22276118 DOI: 10.1371/journal.pone.0029514 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation