1N45

X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME

Replaces:  1QQ8

Summary for 1N45

• Entry DOI: 10.2210/pdb1n45/pdb
• Related: 1N3U 1QQ8
• Descriptor: heme oxygenase 1, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• Functional Keywords: alpha helices, heme-binding site, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Microsome : P09601
• Total number of polymer chains: 2
• Total formula weight: 55126.27

Authors

Schuller, D.J.,Wilks, A.,Ortiz de Montellano, P.R.,Poulos, T.L. (deposition date: 2002-10-30, release date: 2002-11-13, Last modification date: 2024-02-14)

• Primary citation: Lad, L.,Schuller, D.J.,Shimizu, H.,Friedman, J.,Li, H.,Ortiz de Montellano, P.R.,Poulos, T.L.; Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.; J. Biol. Chem., 278:7834-7843, 2003; PubMed: 12500973; DOI: 10.1074/jbc.M211450200

Experimental method

X-RAY DIFFRACTION (1.5 Å)