2GAZ
 
 | | Mycobacterial lipoglycan presentation by CD1d | | 分子名称: | (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M. | | 登録日 | 2006-03-09 | | 公開日 | 2006-09-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d.
J.Immunol., 177, 2006
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1RK0
 | | Mhc Class I H-2Kb Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Glycoprotein B, ... | | 著者 | Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. | | 登録日 | 2003-11-20 | | 公開日 | 2004-12-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution
J.Exp.Med., 200, 2004
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5WET
 | | Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | | 分子名称: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | 登録日 | 2017-07-10 | | 公開日 | 2017-10-18 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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2VE6
 | | Crystal structure of a Murine MHC class I H2-Db molecule in complex with a photocleavable peptide | | 分子名称: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, SENDAI VIRUS EPITOPE RESIDUES 324-332 MODIFIED AT P7 | | 著者 | Grotenbreg, G.M, Roan, N.R, Guillen, E, Meijers, R, Wang, J.H, Bell, G.W, Starnbach, M.N, Ploegh, H.L. | | 登録日 | 2007-10-17 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery of Cd8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I Mhc Tetramers.
Proc.Natl.Acad.Sci.USA, 105, 2008
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5SWZ
 | | Crystal Structure of NP1-B17 TCR-H2Db-NP complex | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Gras, S, Del Campo, C.M, Farenc, C, Josephs, T.M, Rossjohn, J. | | 登録日 | 2016-08-09 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.
Immunity, 45, 2016
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1FFO
 | | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH SYNTHETIC PEPTIDE GP33 (C9M/K1A) | | 分子名称: | BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ... | | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | | 登録日 | 2000-07-25 | | 公開日 | 2002-12-11 | | 最終更新日 | 2017-02-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Peptidic termini play a significant role in TCR recognition.
J.Immunol., 169, 2002
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6CXA
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1CD1
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8TQ8
 | | Crystal structure of Fab.34.5.8 in complex with MHC-I (H2-Dd) | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Fab.34.5.8 Heavy chain, ... | | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | | 登録日 | 2023-08-06 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction.
J Immunol., 212, 2024
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2FO4
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1NAM
 | | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BM3.3 T Cell Receptor alpha-Chain, BM3.3 T Cell Receptor beta-Chain, ... | | 著者 | Reiser, J.-B, Darnault, C, Gregoire, C, Mosser, T, Mazza, G, Kearnay, A, van der Merwe, P.A, Fontecilla-Camps, J.C, Housset, D, Malissen, B. | | 登録日 | 2002-11-28 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | CDR3 loop flexibility contributes to the degeneracy of TCR recognition
Nat.Immunol., 4, 2003
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3ARB
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1FFN
 | | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M) | | 分子名称: | BETA-2 MICROGLOBULIN, BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | | 登録日 | 2000-07-25 | | 公開日 | 2002-12-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
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2ZOL
 | | Crystal structure of H-2Db in complex with the W513S variant of JHMV epitope S510 | | 分子名称: | 9-meric peptide from Spike glycoprotein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Theodossis, A, Dunstone, M.A, Rossjohn, J. | | 登録日 | 2008-05-22 | | 公開日 | 2008-06-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and biological basis of CTL escape in coronavirus-infected mice.
J Immunol., 180, 2008
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3L3H
 | | X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC | | 分子名称: | 10-mer peptide from Polymerase acidic protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Welland, A, Clements, C.S, Dunstone, M.A, Rossjohn, J. | | 登録日 | 2009-12-17 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
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4PGD
 | | MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAF | | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | | 著者 | Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J. | | 登録日 | 2014-05-01 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3TA3
 | | Structure of the mouse CD1d-Glc-DAG-s2-iNKT TCR complex | | 分子名称: | (2S)-1-(alpha-D-glucopyranosyloxy)-3-(hexadecanoyloxy)propan-2-yl (11Z)-octadec-11-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells.
Plos Biol., 9, 2011
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6G9R
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3NWM
 | | Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes | | 分子名称: | Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric protein | | 著者 | Ramagopal, U.A, Samanta, D, Nathenson, S.G, Almo, S.C. | | 登録日 | 2010-07-09 | | 公開日 | 2011-07-06 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells.
Proc.Natl.Acad.Sci.USA, 108, 2011
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1ZHB
 | | Crystal Structure Of The Murine Class I Major Histocompatibility Complex Of H-2Db, B2-Microglobulin, and a 9-Residue Peptide Derived from rat dopamine beta-monooxigenase | | 分子名称: | 9-mer peptide from Dopamine beta-monooxygenase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Sandalova, T, Michaelsson, J, Harris, R.A, Odeberg, J, Schneider, G, Karre, K, Achour, A. | | 登録日 | 2005-04-25 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity
J.Biol.Chem., 280, 2005
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5WES
 | | Crystal Structure H2-Dd with disulfide-linked 5mer peptide | | 分子名称: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | 登録日 | 2017-07-10 | | 公開日 | 2017-10-18 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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1KJ2
 | | Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Allogeneic H-2Kb MHC Class I Molecule, Beta-2 microglobulin, ... | | 著者 | Reiser, J.-B, Gregoire, C, Darnault, C, Mosser, T, Guimezanes, A, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Mazza, G, Malissen, B, Housset, D. | | 登録日 | 2001-12-04 | | 公開日 | 2002-03-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.
Immunity, 16, 2002
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3O8X
 | | Recognition of Glycolipid Antigen by iNKT Cell TCR | | 分子名称: | (2S,3R)-3-HYDROXY-2-(TETRADECANOYLAMINO)OCTADECYL ALPHA-D-GALACTOPYRANOSIDURONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zajonc, D.M, Li, Y. | | 登録日 | 2010-08-03 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | The V alpha 14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.
J.Exp.Med., 207, 2010
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6MIY
 | | Crystal structure of the mCD1d/xxa (JJ239)/iNKTCR ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Bitra, A, Janssens, J. | | 登録日 | 2018-09-20 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
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1FG2
 | | CRYSTAL STRUCTURE OF THE LCMV PEPTIDIC EPITOPE GP33 IN COMPLEX WITH THE MURINE CLASS I MHC MOLECULE H-2DB | | 分子名称: | BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | | 著者 | Tissot, A.C, Ciatto, C, Mittl, P.R.E, Gruetter, M.G, Plueckthun, A. | | 登録日 | 2000-07-27 | | 公開日 | 2000-10-04 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.754 Å) | | 主引用文献 | Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex.
J.Mol.Biol., 302, 2000
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