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PDB: 165 件

4KGC
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Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM
分子名称: (ethane-1,2-diamine-kappa~2~N,N')[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4,5,6-hexayl]ruthenium, DNA (145-mer), Histone H2A, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-04-29
公開日2014-03-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Nat Commun, 5, 2014
6N1Z
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Importin-9 bound to H2A-H2B
分子名称: Histone H2A, Histone H2B 1.1, Importin-9
著者Tomchick, D.R, Chook, Y.M, Padavannil, A.
登録日2018-11-12
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
3LJA
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BU of 3lja by Molmil
Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome
分子名称: 147mer DNA, Histone H2A, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2010-01-26
公開日2010-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome
J.Mol.Biol., 398, 2010
5ONG
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BU of 5ong by Molmil
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Barth, P.D, Richmond, T.J.
登録日2017-08-03
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
7YI1
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BU of 7yi1 by Molmil
Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome
分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
著者Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
登録日2022-07-14
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
5DNN
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Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Ma, Z, Davey, C.A.
登録日2015-09-10
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
5ONW
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BU of 5onw by Molmil
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer and the two H2A/H2B dimers crosslinked via H2A N38C
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Barth, P.D, Richmond, T.J.
登録日2017-08-04
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
8TOF
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BU of 8tof by Molmil
Rpd3S bound to an H3K36Cme3 modified nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ...
著者Markert, J.W, Vos, S.M, Farnung, L.
登録日2023-08-03
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
7VDT
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BU of 7vdt by Molmil
The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ...
著者Chen, Z.C, Chen, K.J, Yuan, J.J.
登録日2021-09-07
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
6WZ9
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BU of 6wz9 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
分子名称: DNA, Histone H2A, Histone H2B 1.1, ...
著者Halic, M, Bilokapic, S.
登録日2020-05-13
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
5E5A
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BU of 5e5a by Molmil
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
分子名称: C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ...
著者Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M.
登録日2015-10-08
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
5DNM
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BU of 5dnm by Molmil
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Muhammad, R, Davey, C.A.
登録日2015-09-10
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
6K01
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BU of 6k01 by Molmil
Crystal structure of xH2A-H2B
分子名称: Histone H2A, Histone H2B 1.1
著者Liu, Y.R.
登録日2019-05-05
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.839 Å)
主引用文献Crystal structure of xlH2A-H2B
Structure, 2019
4J8X
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BU of 4j8x by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)ruthenium(II)
分子名称: DNA, Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
8KD5
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BU of 8kd5 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8KD3
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BU of 8kd3 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
3MVD
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BU of 3mvd by Molmil
Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle
分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Makde, R.D, England, J.R, Yennawar, H.P, Tan, S.
登録日2010-05-04
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of RCC1 chromatin factor bound to the nucleosome core particle.
Nature, 467, 2010
7OHA
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BU of 7oha by Molmil
nucleosome with TBP and TFIIA bound at SHL +2
分子名称: DNA (122-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-09
公開日2021-07-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
3KUY
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BU of 3kuy by Molmil
DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent
分子名称: 2-[(2R)-oxiran-2-ylmethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, DNA (145-MER), Histone H2A, ...
著者Wu, B, Davey, C.A.
登録日2009-11-28
公開日2010-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent
Nucleic Acids Res., 38, 2010
8KD4
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BU of 8kd4 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1
分子名称: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
著者Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J.
登録日2023-08-09
公開日2023-09-13
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
8EU2
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BU of 8eu2 by Molmil
Class3 of the INO80-Hexasome complex
分子名称: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
登録日2022-10-18
公開日2023-07-12
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8G6G
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BU of 8g6g by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 5
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
3LEL
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BU of 3lel by Molmil
Structural Insight into the Sequence-Dependence of Nucleosome Positioning
分子名称: 147-MER DNA, Histone H2A, Histone H2B 1.1, ...
著者Wu, B, Vasudevan, D, Davey, C.A.
登録日2010-01-15
公開日2010-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural insight into the sequence dependence of nucleosome positioning
Structure, 18, 2010
7OH9
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Nucleosome with TBP and TFIIA bound at SHL -6
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-09
公開日2021-07-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
4YS3
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BU of 4ys3 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-03-16
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015

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件を2024-07-10に公開中

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