6WZ9
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Summary for 6WZ9
| Entry DOI | 10.2210/pdb6wz9/pdb |
| EMDB information | 21970 21971 |
| Descriptor | Histone H3.2, Histone H4, Histone H2A, ... (6 entities in total) |
| Functional Keywords | dna repair, parp1, parp2, hpf1, adp-ribosylation, chromatin, histone modifications, gene regulation |
| Biological source | Xenopus laevis (African clawed frog) More |
| Total number of polymer chains | 10 |
| Total formula weight | 211247.00 |
| Authors | Halic, M.,Bilokapic, S. (deposition date: 2020-05-13, release date: 2020-09-16, Last modification date: 2024-03-06) |
| Primary citation | Bilokapic, S.,Suskiewicz, M.J.,Ahel, I.,Halic, M. Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature, 585:609-613, 2020 Cited by PubMed: 32939087DOI: 10.1038/s41586-020-2725-7 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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