6WZ9
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 135 | 15303.9 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (D, H) | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 5 | I (I) | DNA | polymer | 167 | 51776.0 | 1 | synthetic construct | ||
| 6 | J (J) | DNA | polymer | 167 | 51330.7 | 1 | synthetic construct |
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
D, H: 1 - 122 (UniProt: P02281)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | variant |
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 211247.0 | |
| All* | Total formula weight | 211247.0 |
