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PDB: 1180 件

4GKN
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A2-MHC Complex carrying FATGIGIITV
分子名称: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
著者Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
登録日2012-08-13
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4PJD
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BU of 4pjd by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
8GOM
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SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-HLA-A2
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 specific private TCR RLQ7 alpha, ...
著者Wu, D, Mariuzza, R.A.
登録日2022-08-25
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.783 Å)
主引用文献Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity.
J.Biol.Chem., 299, 2023
5XOT
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Crystal structure of pHLA-B35 in complex with TU55 T cell receptor
分子名称: An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2017-05-31
公開日2017-06-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.787 Å)
主引用文献Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
5WWU
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Crystal Structure of HLA-A*2402 in complex with 2009 pandemic influenza A(H1N1) virus and avian influenza A(H5N1) virus-derived peptide H1-25
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F.
登録日2017-01-05
公開日2018-01-17
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Mbio, 9, 2018
3QZW
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BU of 3qzw by Molmil
Plasticity of human CD8 binding to peptide-HLA-A*2402
分子名称: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2011-03-07
公開日2011-06-29
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402
Mol.Immunol., 48, 2011
4I48
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BU of 4i48 by Molmil
Structure of HLA-A68 complexed with an HIV Env derived peptide
分子名称: 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F.
登録日2012-11-27
公開日2013-10-02
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
1DE4
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BU of 1de4 by Molmil
HEMOCHROMATOSIS PROTEIN HFE COMPLEXED WITH TRANSFERRIN RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, CALCIUM ION, ...
著者Bennett, M.J, Lebron, J.A, Bjorkman, P.J.
登録日1999-11-12
公開日2000-01-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.
Nature, 403, 2000
3I6K
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Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Liu, J, Sun, Y, Qi, J, Chu, F, Wu, H, Gao, F, Li, T, Yan, J, Gao, G.F.
登録日2009-07-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
8BP6
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Structure of MHC-class I related molecule MR1 with bound M3Ade
分子名称: (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde, Beta-2-microglobulin,Major histocompatibility complex class I-related gene protein
著者Berloffa, G, Jakob, R.P, Maier, T.
登録日2022-11-16
公開日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The carbonyl nucleoside adduct M3Ade stabilizes MR1 and activates MR1-restricted self- and tumor-reactive T cells
To Be Published
1IM9
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Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1 bound to its MHC ligand HLA-Cw4
分子名称: Beta-2 microglobulin, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, CW-4 CW*0401 ALPHA CHAIN, ...
著者Fan, Q.R, Long, E.O, Wiley, D.C.
登録日2001-05-10
公開日2001-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.
Nat.Immunol., 2, 2001
4X6C
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BU of 4x6c by Molmil
CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
分子名称: (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-12-08
公開日2015-01-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
3D3V
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BU of 3d3v by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
登録日2008-05-12
公開日2009-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner.
Biochem.J., 423, 2009
5W69
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HLA-C*06:02 presenting ARFNDLRFV
分子名称: ALA-ARG-PHE-ASN-ASP-LEU-ARG-PHE-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mobbs, J.I, Vivian, J.P, Rossjohn, J.
登録日2017-06-16
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.
J. Biol. Chem., 292, 2017
1I7T
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BU of 1i7t by Molmil
CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-5V
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2021-07-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
J.Biol.Chem., 276, 2001
8A7Q
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BU of 8a7q by Molmil
beta-2-microglobulin V27M amyloid fibril form 4PF
分子名称: Beta-2-microglobulin
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
4RA3
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Crystal structure of dimeric S33C beta-2 microglobulin mutant in complex with Thioflavin (ThT) at 2.8 Angstrom resolution
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Beta-2-microglobulin
著者Halabelian, L, Bolognesi, M, Ricagno, S.
登録日2014-09-09
公開日2015-09-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A covalent homodimer probing early oligomers along amyloid aggregation.
Sci Rep, 5, 2015
2BCK
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BU of 2bck by Molmil
Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F.
登録日2005-10-19
公開日2006-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
1KPR
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BU of 1kpr by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ...
著者Holmes, M.A, Strong, R.K.
登録日2002-01-02
公開日2003-02-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
7EU2
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BU of 7eu2 by Molmil
Complex structure of HLA0201 with recognizing SARS-CoV-2 epitope S1
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 T-cell Epitope S1
著者Deng, S, Jin, T.
登録日2021-05-15
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Profiling CD8 + T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants.
Cell Rep, 36, 2021
1ZVS
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Crystal structure of the first class MHC mamu and Tat-Tl8 complex
分子名称: Beta-2-microglobulin, MHC class I antigen, Tat-Tl8
著者Lou, Z, Chu, F, Gao, G.F, Rao, Z.
登録日2005-06-02
公開日2006-06-13
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape.
J Immunol., 178, 2007
1I1F
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Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt variant peptide i1y
分子名称: PROTEIN (BETA 2-MICROGLOBULIN), PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-A0201 ALPHA CHAIN), ...
著者Kirksey, T.J, Pogue-Caley, R.R, Frelinger, J.A, Collins, E.J.
登録日1999-04-16
公開日2000-01-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes.
J.Biol.Chem., 274, 1999
3FFC
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BU of 3ffc by Molmil
Crystal Structure of CF34 TCR in complex with HLA-B8/FLR
分子名称: Beta-2-microglobulin, CADMIUM ION, CF34 alpha chain, ...
著者Gras, S, Burrows, S.R, Kjer-Nielsen, L, Clements, C.S, Liu, Y.C, Sullivan, L.C, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2008-12-03
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The shaping of T cell receptor recognition by self-tolerance.
Immunity, 30, 2009
1XZ0
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Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ...
著者Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A.
登録日2004-11-11
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Mechanism of Lipopeptide Presentation by CD1a.
Immunity, 22, 2005
1QSE
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STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R
分子名称: PROTEIN (MHC class I HLA-A), PROTEIN (beta-2 microglobulin), PROTEIN (human T-Cell receptor), ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-21
公開日1999-12-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999

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