2Z62
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![BU of 2z62 by Molmil](/molmil-images/mine/2z62) | Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ... | 著者 | Lee, J.-O, Kim, H.M, Park, B.S. | 登録日 | 2007-07-22 | 公開日 | 2007-09-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130, 2007
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2Z81
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![BU of 2z81 by Molmil](/molmil-images/mine/2z81) | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | 分子名称: | (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, ... | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | 登録日 | 2007-08-30 | 公開日 | 2007-10-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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2Z80
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![BU of 2z80 by Molmil](/molmil-images/mine/2z80) | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, Variable lymphocyte receptor B | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | 登録日 | 2007-08-30 | 公開日 | 2007-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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2Z66
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![BU of 2z66 by Molmil](/molmil-images/mine/2z66) | Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ... | 著者 | Lee, J.-O, Kim, H.M, Park, B.S. | 登録日 | 2007-07-22 | 公開日 | 2007-09-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130, 2007
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7NUW
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![BU of 7nuw by Molmil](/molmil-images/mine/7nuw) | Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions) | 分子名称: | Toll-like receptor 1 | 著者 | Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I. | 登録日 | 2021-03-15 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions. Commun Biol, 4, 2021
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2Z63
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![BU of 2z63 by Molmil](/molmil-images/mine/2z63) | Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ... | 著者 | Kim, H.M, Park, B.S, Lee, J.-O. | 登録日 | 2007-07-22 | 公開日 | 2007-09-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130, 2007
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2Z7X
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![BU of 2z7x by Molmil](/molmil-images/mine/2z7x) | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | 登録日 | 2007-08-29 | 公開日 | 2007-10-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130, 2007
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5GY2
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![BU of 5gy2 by Molmil](/molmil-images/mine/5gy2) | |
7MLM
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![BU of 7mlm by Molmil](/molmil-images/mine/7mlm) | Crystal structure of mouse TLR4/MD-2 in complex with sulfatides | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Su, L, Beutler, B. | 登録日 | 2021-04-28 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Sulfatides are endogenous ligands for the TLR4-MD-2 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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4QXE
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![BU of 4qxe by Molmil](/molmil-images/mine/4qxe) | |
4QXF
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![BU of 4qxf by Molmil](/molmil-images/mine/4qxf) | |
6BXA
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![BU of 6bxa by Molmil](/molmil-images/mine/6bxa) | Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R. | 登録日 | 2017-12-18 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430, 2018
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6NIH
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![BU of 6nih by Molmil](/molmil-images/mine/6nih) | Crystal structure of human TLR1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Su, L, Zhang, H. | 登録日 | 2018-12-27 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim. J. Med. Chem., 62, 2019
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2O6R
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![BU of 2o6r by Molmil](/molmil-images/mine/2o6r) | |
4BV4
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![BU of 4bv4 by Molmil](/molmil-images/mine/4bv4) | Structure and allostery in Toll-Spatzle recognition | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN SPAETZLE C-106, PROTEIN TOLL, ... | 著者 | Lewis, M.F, Arnot, C.J, Beeston, H, McCoy, A, Ashcroft, A.E, Gay, N.J, Gangloff, M. | 登録日 | 2013-06-24 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cytokine Spatzle Binds to the Drosophila Immunoreceptor Toll with a Neurotrophin-Like Specificity and Couples Receptor Activation. Proc.Natl.Acad.Sci.USA, 110, 2013
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3UL7
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![BU of 3ul7 by Molmil](/molmil-images/mine/3ul7) | Crystal structure of the TV3 mutant F63W | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-11-10 | 公開日 | 2012-04-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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4QDH
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![BU of 4qdh by Molmil](/molmil-images/mine/4qdh) | |
3A7C
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![BU of 3a7c by Molmil](/molmil-images/mine/3a7c) | Crystal structure of TLR2-PE-DTPA complex | 分子名称: | (10S,13R)-3-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-10-hydroxy-5,16-dioxo-13-(tetradecanoyloxy)-9,11,15-trioxa-3,6-diaza-10-phosphanonacosan-1-oic acid 10-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kang, J.Y, Jin, M.S, Lee, J.-O. | 登録日 | 2009-09-20 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer Immunity, 31, 2009
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4ARN
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![BU of 4arn by Molmil](/molmil-images/mine/4arn) | |
3UL9
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![BU of 3ul9 by Molmil](/molmil-images/mine/3ul9) | structure of the TV3 mutant M41E | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-11-10 | 公開日 | 2012-05-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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7NUX
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![BU of 7nux by Molmil](/molmil-images/mine/7nux) | Crystal structure of the TIR domain of human TLR1 (crystallised without ZN2+ ions) | 分子名称: | Toll-like receptor 1 | 著者 | Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I. | 登録日 | 2021-03-15 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions. Commun Biol, 4, 2021
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3V47
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![BU of 3v47 by Molmil](/molmil-images/mine/3v47) | Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Flagellin, ... | 著者 | Yoon, S.I, Hong, H, Wilson, I.A. | 登録日 | 2011-12-14 | 公開日 | 2012-02-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Structural basis of TLR5-flagellin recognition and signaling. Science, 335, 2012
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3UL8
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![BU of 3ul8 by Molmil](/molmil-images/mine/3ul8) | Crystal structure of the TV3 mutant V134L | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-11-10 | 公開日 | 2012-04-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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6BXC
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![BU of 6bxc by Molmil](/molmil-images/mine/6bxc) | Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R. | 登録日 | 2017-12-18 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430, 2018
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3A7B
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![BU of 3a7b by Molmil](/molmil-images/mine/3a7b) | Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex | 分子名称: | (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kang, J.Y, Jin, M.S, Lee, J.-O. | 登録日 | 2009-09-20 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer Immunity, 31, 2009
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