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PDB: 36 件
2Z62
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Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ...
著者Lee, J.-O, Kim, H.M, Park, B.S.
登録日2007-07-22
公開日2007-09-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2Z81
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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
分子名称: (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, ...
著者Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y.
登録日2007-08-30
公開日2007-10-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
2Z80
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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, Variable lymphocyte receptor B
著者Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y.
登録日2007-08-30
公開日2007-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
2Z66
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Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
著者Lee, J.-O, Kim, H.M, Park, B.S.
登録日2007-07-22
公開日2007-09-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
7NUW
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BU of 7nuw by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions)
分子名称: Toll-like receptor 1
著者Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
登録日2021-03-15
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
2Z63
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BU of 2z63 by Molmil
Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ...
著者Kim, H.M, Park, B.S, Lee, J.-O.
登録日2007-07-22
公開日2007-09-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2Z7X
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BU of 2z7x by Molmil
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ...
著者Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y.
登録日2007-08-29
公開日2007-10-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
5GY2
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Crystal structure of a complex between Bacillus subtilis flagellin and zebrafish Toll-like receptor 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Flagellin, ...
著者Song, W.S, Yoon, S.I.
登録日2016-09-21
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A conserved TLR5 binding and activation hot spot on flagellin
Sci Rep, 7, 2017
7MLM
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Crystal structure of mouse TLR4/MD-2 in complex with sulfatides
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Su, L, Beutler, B.
登録日2021-04-28
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Sulfatides are endogenous ligands for the TLR4-MD-2 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
4QXE
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BU of 4qxe by Molmil
Crystal structure of LGR4 fused with hagfish VLR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Xu, J.G, Huang, C, Zhu, Y.
登録日2014-07-20
公開日2014-10-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of LGR4 fused with hagfish VLR
TO BE PUBLISHED
4QXF
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crystal structure of human LGR4 and Rspo1
分子名称: Leucine-rich repeat-containing G-protein coupled receptor 4, Variable lymphocyte receptor B, R-spondin-1
著者Xu, J.G, Huang, C, Zhou, Y, Zhu, Y.
登録日2014-07-20
公開日2014-10-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献crystal structure of human LGR4 and Rspo1
TO BE PUBLISHED
6BXA
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BU of 6bxa by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
登録日2017-12-18
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
6NIH
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BU of 6nih by Molmil
Crystal structure of human TLR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Su, L, Zhang, H.
登録日2018-12-27
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim.
J. Med. Chem., 62, 2019
2O6R
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BU of 2o6r by Molmil
Structural diversity of the hagfish Variable Lymphocyte Receptors B61
分子名称: Variable lymphocyte receptor B
著者Lee, J.O, Kim, H.M, Oh, S.C.
登録日2006-12-08
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural diversity of the hagfish variable lymphocyte receptors
J.Biol.Chem., 282, 2007
4BV4
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BU of 4bv4 by Molmil
Structure and allostery in Toll-Spatzle recognition
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN SPAETZLE C-106, PROTEIN TOLL, ...
著者Lewis, M.F, Arnot, C.J, Beeston, H, McCoy, A, Ashcroft, A.E, Gay, N.J, Gangloff, M.
登録日2013-06-24
公開日2013-12-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Cytokine Spatzle Binds to the Drosophila Immunoreceptor Toll with a Neurotrophin-Like Specificity and Couples Receptor Activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
3UL7
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BU of 3ul7 by Molmil
Crystal structure of the TV3 mutant F63W
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ...
著者Kim, H.J, Cheong, H.K, Jeon, Y.H.
登録日2011-11-10
公開日2012-04-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
4QDH
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BU of 4qdh by Molmil
Crystal Structure of the C-terminal Domain of Mouse TLR9
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
著者Collins, B.C, Wilson, I.A.
登録日2014-05-13
公開日2014-06-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
3A7C
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BU of 3a7c by Molmil
Crystal structure of TLR2-PE-DTPA complex
分子名称: (10S,13R)-3-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-10-hydroxy-5,16-dioxo-13-(tetradecanoyloxy)-9,11,15-trioxa-3,6-diaza-10-phosphanonacosan-1-oic acid 10-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kang, J.Y, Jin, M.S, Lee, J.-O.
登録日2009-09-20
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
4ARN
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BU of 4arn by Molmil
Crystal structure of the N-terminal domain of Drosophila Toll receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MALONATE ION, ...
著者Gangloff, M, Gay, N.J.
登録日2012-04-25
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor.
Structure, 21, 2013
3UL9
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structure of the TV3 mutant M41E
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ...
著者Kim, H.J, Cheong, H.K, Jeon, Y.H.
登録日2011-11-10
公開日2012-05-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
7NUX
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BU of 7nux by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised without ZN2+ ions)
分子名称: Toll-like receptor 1
著者Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
登録日2021-03-15
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
3V47
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BU of 3v47 by Molmil
Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Flagellin, ...
著者Yoon, S.I, Hong, H, Wilson, I.A.
登録日2011-12-14
公開日2012-02-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis of TLR5-flagellin recognition and signaling.
Science, 335, 2012
3UL8
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Crystal structure of the TV3 mutant V134L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ...
著者Kim, H.J, Cheong, H.K, Jeon, Y.H.
登録日2011-11-10
公開日2012-04-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
6BXC
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BU of 6bxc by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
登録日2017-12-18
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
3A7B
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Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex
分子名称: (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kang, J.Y, Jin, M.S, Lee, J.-O.
登録日2009-09-20
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009

 

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