7NUW

Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions)

Summary for 7NUW

Entry DOI	10.2210/pdb7nuw/pdb
Descriptor	Toll-like receptor 1 (2 entities in total)
Functional Keywords	toll-like receptor, tir domain, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	19074.96
Authors	Vakhrameev, D.D.,Luginina, A.P.,Shevtsov, M.B.,Lushpa, V.A.,Mineev, K.S.,Borshchevskiy, V.I. (deposition date: 2021-03-15, release date: 2021-08-25, Last modification date: 2024-01-31)
Primary citation	Lushpa, V.A.,Goncharuk, M.V.,Lin, C.,Zalevsky, A.O.,Talyzina, I.A.,Luginina, A.P.,Vakhrameev, D.D.,Shevtsov, M.B.,Goncharuk, S.A.,Arseniev, A.S.,Borshchevskiy, V.I.,Wang, X.,Mineev, K.S. Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions. Commun Biol, 4:1003-1003, 2021 Cited by PubMed: 34429510 DOI: 10.1038/s42003-021-02532-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation