2Z62

Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61

Summary for 2Z62

• Entry DOI: 10.2210/pdb2z62/pdb
• Related: 2Z63 2Z64 2Z65 2Z66
• Descriptor: Toll-like receptor 4, Variable lymphocyte receptor B, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: tlr, toll-like receptor, vlr hybrid, md-2, lps, glycoprotein, immune response, inflammatory response, innate immunity, leucine-rich repeat, membrane, transmembrane, immune system
• Biological source: Homo sapiens (human, inshore hagfish); More
• Total number of polymer chains: 1
• Total formula weight: 32869.34

Authors

Lee, J.-O.,Kim, H.M.,Park, B.S. (deposition date: 2007-07-22, release date: 2007-09-18, Last modification date: 2023-11-01)

• Primary citation: Kim, H.M.,Park, B.S.,Kim, J.-I.,Kim, S.E.,Lee, J.,Oh, S.C.,Enkhbayar, P.,Matsushima, N.,Lee, H.,Yoo, O.J.,Lee, J.-O.; Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran; Cell(Cambridge,Mass.), 130:906-917, 2007; PubMed: 17803912; DOI: 10.1016/j.cell.2007.08.002

Experimental method

X-RAY DIFFRACTION (1.7 Å)