2Z63

Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61

Summary for 2Z63

Entry DOI	10.2210/pdb2z63/pdb
Related	2Z62 2Z64 2Z65 2Z66
Descriptor	Toll-like receptor 4, Variable lymphocyte receptor B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	tlr4, toll-like receptor, md-2, lps, immune system
Biological source	Homo sapiens (human, inshore hagfish) More
Total number of polymer chains	1
Total formula weight	65490.38
Authors	Kim, H.M.,Park, B.S.,Lee, J.-O. (deposition date: 2007-07-22, release date: 2007-09-18, Last modification date: 2023-11-01)
Primary citation	Kim, H.M.,Park, B.S.,Kim, J.-I.,Kim, S.E.,Lee, J.,Oh, S.C.,Enkhbayar, P.,Matsushima, N.,Lee, H.,Yoo, O.J.,Lee, J.-O. Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130:906-917, 2007 Cited by PubMed: 17803912 DOI: 10.1016/j.cell.2007.08.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation