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PDB: 57 件
1MB6
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Three dimensional solution structure of huwentoxin-IV by 2D 1H-NMR
分子名称: huwentoxin-iv
著者Peng, K, Shu, Q, Liang, S.P.
登録日2002-08-02
公開日2002-08-21
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena
J.Biol.Chem., 277, 2002
5EPM
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Ceratotoxin variant in complex with specific antibody Fab fragment
分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Beta-theraphotoxin-Cm1a
著者Strop, P, Shcherbatko, A, Rossi, A.
登録日2015-11-11
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain.
J.Biol.Chem., 291, 2016
6MK5
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Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1
分子名称: Toxin GTx1-15
著者Schroeder, C.I.
登録日2018-09-25
公開日2018-12-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1.
ACS Chem. Biol., 14, 2019
2WH9
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Solution structure of GxTX-1E
分子名称: GUANGXITOXIN-1EGXTX-1E
著者Lee, S.K, Jung, H.H, Lee, J.Y, Lee, C.W, Kim, J.I.
登録日2009-05-02
公開日2010-05-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels.
Biochemistry, 49, 2010
6GFT
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Antinociceptive evaluation of cyriotoxin-1a, the first toxin purified from Cyriopagopus schioedtei spider venom
分子名称: cyriotoxin-1a
著者Kurz, M.
登録日2018-05-02
公開日2019-03-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei.
Br.J.Pharmacol., 176, 2019
2JTB
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Three dimensional solution structure of hainantoxin-III by 2D 1H-NMR
分子名称: Hainantoxin-3
著者Zhu, Q, Liu, Z, Liang, S.
登録日2007-07-25
公開日2007-08-21
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Three dimensional solution structure of hainantoxin-III by 2D 1H-NMR
To be Published
8FEY
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Solution structure of Pmu1a
分子名称: Pmu1a toxin
著者Daly, N.L, Wilson, D.T.
登録日2022-12-07
公開日2023-03-29
最終更新日2023-08-02
実験手法SOLUTION NMR
主引用文献Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa V 1.7 and hCa V 3 voltage-gated channels.
Febs J., 290, 2023
8FD4
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Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
分子名称: Jingzhaotoxin F7-10.36
著者Sharma, G, Jia, X, Chin, Y.K.Y, Mobli, M.
登録日2022-12-01
公開日2023-11-08
実験手法SOLUTION NMR
主引用文献Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao
To Be Published
2I1T
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Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels
分子名称: Jingzhaotoxin-3
著者Liao, Z, Peng, K, Liang, S.
登録日2006-08-15
公開日2006-08-29
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels
To be Published
1D1H
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SOLUTION STRUCTURE OF HANATOXIN 1
分子名称: HANATOXIN TYPE 1
著者Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I.
登録日1999-09-16
公開日2000-09-20
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.
J.Mol.Biol., 297, 2000
5I2P
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Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering)
分子名称: W7A mu-TRTX-Pre1a Toxin
著者Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
登録日2016-02-09
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a
To Be Published
5I1X
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Resonance assignments and NMR structure determination of tarantula toxin, F8A mutant of beta-TRTX-Pre1a
分子名称: mu-TRTX-Pre1a toxin
著者Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
登録日2016-02-07
公開日2017-02-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Resonance assignments and NMR structure determination of tarantula toxin, mu-TRTX-Pre1a
To Be Published
6V6T
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Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
分子名称: Delta-theraphotoxin-Hm1b
著者Chin, Y.K.Y, Chow, C.Y, King, G.F.
登録日2019-12-05
公開日2020-05-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
5T3M
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Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7
分子名称: Mu-theraphotoxin-Hs2a
著者Rahnama, S, Sharma, G, Mobli, M.
登録日2016-08-25
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.
PLoS ONE, 12, 2017
5TLR
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Solution NMR structure of gHwTx-IV
分子名称: Mu-theraphotoxin-Hs2a
著者Agwa, A.J, Schroeder, C.I.
登録日2016-10-11
公開日2017-02-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.
Biochim. Biophys. Acta, 1859, 2017
5WE3
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Solution NMR structure of PaurTx-3
分子名称: Beta-theraphotoxin-Ps1a
著者Agwa, A.J, Schroeder, C.I.
登録日2017-07-06
公開日2017-09-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins.
Toxins (Basel), 9, 2017
5WLX
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Solution structure of kappa-theraphotoxin-Aa1a
分子名称: Kappa-theraphotoxin-Aa1a
著者Chin, Y.K.Y, Ma, L, King, G.F.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
1EMX
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SOLUTION STRUCTURE OF HPTX2, A TOXIN FROM HETEROPODA VENATORIA SPIDER VENOM THAT BLOCKS KV4.2 POTASSIUM CHANNEL
分子名称: HETEROPODATOXIN 2
著者Bernard, C, Legros, C, Ferrat, G, Bishoff, U, Marquardt, A, Pongs, O, Darbon, H.
登録日2000-03-20
公開日2001-01-24
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel.
Protein Sci., 9, 2000
6AV8
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Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
分子名称: U5-theraphotoxin-Hs1b 1
著者Gewe, M.M, Rupert, P, Strong, R.K.
登録日2017-09-01
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
6BTV
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Solution NMR structures for CcoTx-II
分子名称: Beta-theraphotoxin-Cm1b
著者Agwa, A.J, Schroeder, C.I.
登録日2017-12-07
公開日2018-05-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
6BR0
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Solution NMR structure for CcoTx-I
分子名称: Beta-theraphotoxin-Cm1a
著者Agwa, A.J, Schroeder, C.I.
登録日2017-11-29
公開日2018-05-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
J. Biol. Chem., 293, 2018
1ZJQ
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Solution structure of Jingzhaotoxin-VII
分子名称: Jingzhaotoxin-VII
著者Liao, Z.
登録日2005-04-30
公開日2005-05-24
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of Jingzhaotoxin-VII
TO BE PUBLISHED
2A2V
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The solution structure of Jingzhaotoxin-XI
分子名称: Jingzhaotoxin-XI
著者Liao, Z, Liang, S.P.
登録日2005-06-23
公開日2005-07-05
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The solution structure of Jingzhaotoxin-XI
To be published
2AAP
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Solution structure of jingzhaotoxin-vii
分子名称: Jingzhaotoxin-Vii
著者Liao, Z, Liang, S.P.
登録日2005-07-14
公開日2005-08-02
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of jingzhaotoxin-vii
TO BE PUBLISHED
1NIX
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-I BY 2D 1H-NMR
分子名称: HAINANTOXIN-I
著者Li, D, Liang, S.
登録日2002-12-29
公開日2003-01-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana.
Febs Lett., 555, 2003

 

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