Three dimensional solution structure of huwentoxin-IV by 2D 1H-NMR

Summary for 1MB6

Descriptorhuwentoxin-iv (1 entity in total)
Functional Keywordscontaining a double-stranded beta-sheet and four beta-turns, toxin
Biological sourceOrnithoctonus huwena (Chinese earth tiger)
Cellular locationSecreted  P83303
Total number of polymer chains1
Total molecular weight4120.87
Peng, K.,Shu, Q.,Liang, S.P. (deposition date: 2002-08-02, release date: 2002-08-21, Last modification date: 2017-11-29)
Primary citation
Peng, K.,Shu, Q.,Liu, Z.,Liang, S.P.
Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena
J.Biol.Chem., 277:47564-47571, 2002
PubMed: 12228241 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M204063200
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers80 24.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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PDB entries from 2020-11-25