6EYD
| Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Kouba, T, Barvik, I, Krasny, L. | 登録日 | 2017-11-11 | 公開日 | 2018-12-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
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7KHE
| Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp | 分子名称: | CHAPSO, DNA (46-MER), DNA (54-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-21 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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8HVR
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8HIH
| Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Shi, J, Xu, J.C. | 登録日 | 2022-11-20 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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6FBV
| Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Das, K, Lin, W, Ebright, E. | 登録日 | 2017-12-19 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
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8IGR
| Cryo-EM structure of CII-dependent transcription activation complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. | 登録日 | 2023-02-21 | 公開日 | 2023-05-17 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
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8IGS
| Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. | 登録日 | 2023-02-21 | 公開日 | 2023-05-17 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
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7KIF
| Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor | 分子名称: | DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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7KIM
| Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor | 分子名称: | DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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7KIN
| Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter | 分子名称: | DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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8JO2
| Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA | 分子名称: | DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. | 登録日 | 2023-06-06 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
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6DVD
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11 | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.899 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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8JKE
| AfsR(T337A) transcription activation complex | 分子名称: | DNA(65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Wang, Y, Zheng, J. | 登録日 | 2023-06-01 | 公開日 | 2024-02-14 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces. Plos Biol., 22, 2024
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7L7B
| Clostridioides difficile RNAP with fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J. | 登録日 | 2020-12-28 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature, 604, 2022
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7KHI
| Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp | 分子名称: | CHAPSO, DNA (28-MER), DNA (36-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-21 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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7KHB
| Escherichia coli RNA polymerase and rrnBP1 promoter open complex | 分子名称: | CHAPSO, DNA (60-MER), DNA (64-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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7KHC
| Escherichia coli RNA polymerase and rrnBP1 promoter closed complex | 分子名称: | CHAPSO, DNA (18 MER), DNA (63-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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5W1T
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5VOI
| X-ray crystal structure of bacterial RNA polymerase and pyrG promoter complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. | 登録日 | 2017-05-02 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5YIX
| Caulobacter crescentus GcrA sigma-interacting domain (SID) in complex with domain 2 of sigma 70 | 分子名称: | (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, RNA polymerase sigma factor RpoD, ... | 著者 | Wu, X, Zhang, Y. | 登録日 | 2017-10-06 | 公開日 | 2018-03-21 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
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5XJ0
| T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76 | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Ooi, W.Y, Murayama, Y, Mekler, V, Minakhin, L, Severinov, K, Yokoyama, S, Sekine, S. | 登録日 | 2017-04-28 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.004 Å) | 主引用文献 | A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation Nucleic Acids Res., 46, 2018
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5W1S
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5X21
| Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) | 分子名称: | (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zhang, Y, Ebright, R. | 登録日 | 2017-01-29 | 公開日 | 2017-07-05 | 最終更新日 | 2022-10-12 | 実験手法 | X-RAY DIFFRACTION (3.323 Å) | 主引用文献 | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
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5X22
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6WOX
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