5XJ0

T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76

Summary for 5XJ0

Entry DOI	10.2210/pdb5xj0/pdb
Related	3WOD
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	transcription regulation by bacteriophage-encoded proteins, transferase-transcription complex, transferase/transcription
Biological source	Thermus virus P23-45 More
Cellular location	Cytoplasm : Q5SKW1
Total number of polymer chains	9
Total formula weight	465889.38
Authors	Ooi, W.Y.,Murayama, Y.,Mekler, V.,Minakhin, L.,Severinov, K.,Yokoyama, S.,Sekine, S. (deposition date: 2017-04-28, release date: 2017-12-20, Last modification date: 2023-11-22)
Primary citation	Ooi, W.Y.,Murayama, Y.,Mekler, V.,Minakhin, L.,Severinov, K.,Yokoyama, S.,Sekine, S.I. A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation Nucleic Acids Res., 46:431-441, 2018 Cited by PubMed: 29165680 DOI: 10.1093/nar/gkx1162 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.004 Å)

Structure validation