5XJ0
T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76
Summary for 5XJ0
Entry DOI | 10.2210/pdb5xj0/pdb |
Related | 3WOD |
Descriptor | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total) |
Functional Keywords | transcription regulation by bacteriophage-encoded proteins, transferase-transcription complex, transferase/transcription |
Biological source | Thermus virus P23-45 More |
Cellular location | Cytoplasm : Q5SKW1 |
Total number of polymer chains | 9 |
Total formula weight | 465889.38 |
Authors | Ooi, W.Y.,Murayama, Y.,Mekler, V.,Minakhin, L.,Severinov, K.,Yokoyama, S.,Sekine, S. (deposition date: 2017-04-28, release date: 2017-12-20, Last modification date: 2023-11-22) |
Primary citation | Ooi, W.Y.,Murayama, Y.,Mekler, V.,Minakhin, L.,Severinov, K.,Yokoyama, S.,Sekine, S.I. A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation Nucleic Acids Res., 46:431-441, 2018 Cited by PubMed: 29165680DOI: 10.1093/nar/gkx1162 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.004 Å) |
Structure validation
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