3GMH
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![BU of 3gmh by Molmil](/molmil-images/mine/3gmh) | Crystal Structure of the Mad2 Dimer | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION | 著者 | Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J. | 登録日 | 2009-03-13 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Structure of an intermediate conformer of the spindle checkpoint protein Mad2. Proc.Natl.Acad.Sci.USA, 112, 2015
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6EKM
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8CXK
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![BU of 8cxk by Molmil](/molmil-images/mine/8cxk) | Structure of the C. elegans HIM-3 R93Y mutant | 分子名称: | HORMA domain-containing protein | 著者 | Ego, K.M, Russo, A, Giacopazzi, S, Deshong, A, Menon, M, Ortiz, V, Bhalla, N, Corbett, K.D. | 登録日 | 2022-05-21 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans. Plos Genet., 19, 2023
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1S2H
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![BU of 1s2h by Molmil](/molmil-images/mine/1s2h) | The Mad2 spindle checkpoint protein possesses two distinct natively folded states | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2A | 著者 | Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H. | 登録日 | 2004-01-08 | 公開日 | 2004-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat.Struct.Mol.Biol., 11, 2004
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6M7A
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1DUJ
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![BU of 1duj by Molmil](/molmil-images/mine/1duj) | SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 | 分子名称: | SPINDLE ASSEMBLY CHECKPOINT PROTEIN | 著者 | Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. | 登録日 | 2000-01-17 | 公開日 | 2000-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat.Struct.Biol., 7, 2000
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5O8K
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8J69
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6M7B
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![BU of 6m7b by Molmil](/molmil-images/mine/6m7b) | |
5XPT
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5XPU
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1GO4
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![BU of 1go4 by Molmil](/molmil-images/mine/1go4) | Crystal structure of Mad1-Mad2 reveals a conserved Mad2 binding motif in Mad1 and Cdc20. | 分子名称: | Mitotic spindle assembly checkpoint protein MAD1, Mitotic spindle assembly checkpoint protein MAD2A | 著者 | Sironi, L, Mapelli, M, Jeang, K.T, Musacchio, A. | 登録日 | 2001-10-17 | 公開日 | 2002-05-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J., 21, 2002
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6NIF
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![BU of 6nif by Molmil](/molmil-images/mine/6nif) | crystal structure of human REV7-RAN complex | 分子名称: | hREV7, GTP-binding nuclear protein Ran, hREV3 fusion | 著者 | Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | 登録日 | 2018-12-27 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
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3ABD
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![BU of 3abd by Molmil](/molmil-images/mine/3abd) | Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal | 分子名称: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | 著者 | Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M. | 登録日 | 2009-12-07 | 公開日 | 2010-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1 J.Biol.Chem., 285, 2010
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3ABE
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![BU of 3abe by Molmil](/molmil-images/mine/3abe) | Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal | 分子名称: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | 著者 | Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M. | 登録日 | 2009-12-07 | 公開日 | 2010-02-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1 J.Biol.Chem., 285, 2010
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1KLQ
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![BU of 1klq by Molmil](/molmil-images/mine/1klq) | The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20 | 分子名称: | MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide | 著者 | Luo, X, Tang, Z, Rizo, J, Yu, H. | 登録日 | 2001-12-12 | 公開日 | 2002-01-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol.Cell, 9, 2002
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6EKJ
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6EKL
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6BCD
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![BU of 6bcd by Molmil](/molmil-images/mine/6bcd) | Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014) | 分子名称: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | 著者 | Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. | 登録日 | 2017-10-20 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BC8
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![BU of 6bc8 by Molmil](/molmil-images/mine/6bc8) | Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex | 分子名称: | ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ... | 著者 | Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. | 登録日 | 2017-10-20 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2V64
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![BU of 2v64 by Molmil](/molmil-images/mine/2v64) | Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2. | 分子名称: | MBP1, MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A | 著者 | Mapelli, M, Massimiliano, L, Santaguida, S, Musacchio, A. | 登録日 | 2007-07-13 | 公開日 | 2007-11-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The MAD2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint Cell(Cambridge,Mass.), 131, 2007
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2VFX
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![BU of 2vfx by Molmil](/molmil-images/mine/2vfx) | Structure of the Symmetric Mad2 Dimer | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | 著者 | Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. | 登録日 | 2007-11-05 | 公開日 | 2008-03-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol., 6, 2008
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6BI7
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![BU of 6bi7 by Molmil](/molmil-images/mine/6bi7) | Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions | 分子名称: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | 著者 | Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y. | 登録日 | 2017-11-01 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6K08
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6K07
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![BU of 6k07 by Molmil](/molmil-images/mine/6k07) | Crystal structure of REV7(R124A) in complex with a Shieldin3 fragment | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3 | 著者 | Zhang, F, Dai, Y. | 登録日 | 2019-05-05 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair. J.Biol.Chem., 295, 2020
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