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PDB: 44 件

2LVW
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Solution NMR studies of the dimeric regulatory subunit IlvN of the E.coli Acetohydroxyacid synthase I (AHAS I)
分子名称: Acetolactate synthase isozyme 1 small subunit
著者Karanth, M.N, Sarma, S.P.
登録日2012-07-12
公開日2013-05-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The coil-to-helix transition in IlvN regulates the allosteric control of Escherichia coli acetohydroxyacid synthase I
Biochemistry, 52, 2013
5FII
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Structure of a human aspartate kinase, chorismate mutase and TyrA domain.
分子名称: PHENYLALANINE, PHENYLALANINE-4-HYDROXYLASE
著者Patel, D, Kopec, J, Shrestha, L, Fitzpatrick, F, Pinkas, D, Chaikuad, A, Dixon-Clarke, S, McCorvie, T.J, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
登録日2015-09-25
公開日2016-03-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Ligand-Dependent Dimerization of Phenylalanine Hydroxylase Regulatory Domain.
Sci.Rep., 6, 2016
5YPP
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Crystal structure of IlvN.Val-1a
分子名称: ACETATE ION, Acetolactate synthase isozyme 1 small subunit, DI(HYDROXYETHYL)ETHER, ...
著者Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
登録日2017-11-02
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5YPW
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Crystal structure of IlvN.Val-1b
分子名称: Acetolactate synthase isozyme 1 small subunit, VALINE
著者Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
登録日2017-11-03
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5YPY
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Crystal structure of IlvN. Val-1c
分子名称: Acetolactate synthase isozyme 1 small subunit, VALINE
著者Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
登録日2017-11-04
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.966 Å)
主引用文献Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
5YUM
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Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs
分子名称: Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE
著者Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
登録日2017-11-22
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.432 Å)
主引用文献Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
2RE1
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Crystal structure of aspartokinase alpha and beta subunits
分子名称: Aspartokinase, alpha and beta subunits, CALCIUM ION
著者Chang, C, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-09-25
公開日2007-10-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of aspartokinase alpha and beta subunits.
To be Published
3S1T
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Structure of the regulatory domain of aspartokinase (Rv3709c; AK-beta) in complex with threonine from Mycobacterium tuberculosis
分子名称: Aspartokinase, SULFATE ION, THREONINE
著者Schuldt, L, Mueller-Dieckmann, J, Weiss, M.S.
登録日2011-05-16
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献High-resolution X-ray structure of the regulatory domain of the mycobacterial aspartokinase in complex with threonine
To be Published
6U60
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Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ...
著者Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-08-28
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
5V0S
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Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis
分子名称: CALCIUM ION, Prephenate dehydrogenase, SULFATE ION
著者Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-28
公開日2017-03-08
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
4GO7
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The regulatory subunit of aspartate kinase in complex with threonine from Mycobacterium tuberculosis
分子名称: Aspartokinase, THREONINE
著者Yang, Q, Li, X.
登録日2012-08-19
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
1Y7P
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1.9 A Crystal Structure of a Protein of Unknown Function AF1403 from Archaeoglobus fulgidus, Probable Metabolic Regulator
分子名称: Hypothetical protein AF1403, ZINC ION, beta-D-ribopyranose
著者Zhang, R, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-12-09
公開日2005-02-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1.9A crystal structure of a hypothetical protein AF1403 from Archaeoglobus fulgidus
To be Published
4GO5
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The regulatory subunit of aspartate kinase from Mycobacterium tuberculosis
分子名称: Aspartokinase
著者Yang, Q, Li, X.
登録日2012-08-18
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
5UYY
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Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine
分子名称: Prephenate dehydrogenase, TYROSINE
著者Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-24
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain.
Febs J., 287, 2020
6DZS
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BU of 6dzs by Molmil
Mycobacterial homoserine dehydrogenase ThrA in complex with NADP
分子名称: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Chaton, C.T, Rodriguez, E.S, Korotkov, K.V.
登録日2018-07-05
公開日2018-07-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published
2HMF
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BU of 2hmf by Molmil
Structure of a Threonine Sensitive Aspartokinase from Methanococcus jannaschii Complexed with Mg-ADP and Aspartate
分子名称: ADENOSINE-5'-DIPHOSPHATE, ASPARTIC ACID, MAGNESIUM ION, ...
著者Faehnle, C.R, Viola, R.E.
登録日2006-07-11
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase.
Acta Crystallogr.,Sect.F, 62, 2006
5EGQ
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BU of 5egq by Molmil
Structure of tetrameric rat phenylalanine hydroxylase mutant R270K, residues 25-453
分子名称: Phenylalanine-4-hydroxylase, SULFATE ION
著者Taylor, A.B, Khan, C.A, Fitzpatrick, P.F.
登録日2015-10-27
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.
J.Am.Chem.Soc., 138, 2016
1VR9
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BU of 1vr9 by Molmil
CRYSTAL STRUCTURE OF A CBS DOMAIN PAIR/ACT DOMAIN PROTEIN (TM0892) FROM THERMOTOGA MARITIMA AT 1.70 A RESOLUTION
分子名称: CBS domain protein/ACT domain protein
著者Joint Center for Structural Genomics (JCSG)
登録日2005-02-17
公開日2005-03-15
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of CBS domain protein/ACT domain protein (TM0892) from Thermotoga maritima at 1.70 A resolution
To be published
1PHZ
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BU of 1phz by Molmil
STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE
分子名称: FE (III) ION, PROTEIN (PHENYLALANINE HYDROXYLASE)
著者Kobe, B, Jennings, I.G, House, C.M, Michell, B.J, Cotton, R.G, Kemp, B.E.
登録日1998-11-11
公開日1999-04-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of autoregulation of phenylalanine hydroxylase.
Nat.Struct.Biol., 6, 1999
5DEN
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The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
分子名称: FE (III) ION, Phenylalanine-4-hydroxylase
著者Arturo, E.C, Loll, P.J, Jaffe, E.K.
登録日2015-08-25
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Proc.Natl.Acad.Sci.USA, 113, 2016
6WO1
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Hybrid acetohydroxyacid synthase complex structure with Cryptococcus neoformans AHAS catalytic subunit and Saccharomyces cerevisiae AHAS regulatory subunit
分子名称: 2-methylpyrimidin-4-amine, Acetohydroxyacid synthase catalytic subunit, Acetohydroxyacid synthase regulatory subunit, ...
著者Guddat, L.W, Lonhienne, T.
登録日2020-04-23
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
3W7B
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BU of 3w7b by Molmil
Crystal structure of formyltetrahydrofolate deformylase from Thermus thermophilus HB8
分子名称: Formyltetrahydrofolate deformylase
著者Sampei, G, Yanagida, Y, Ogata, N, Kusano, M, Terao, K, Kawai, H, Fukai, Y, Kanagawa, M, Inoue, Y, Baba, S, Kawai, G.
登録日2013-02-28
公開日2014-01-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures and reaction mechanisms of the two related enzymes, PurN and PurU
J.Biochem., 154, 2013
3C20
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Crystal Structure of Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-aspartate
分子名称: ASPARTIC ACID, FORMIC ACID, Probable aspartokinase
著者Liu, X, Pavlovsky, A.G, Viola, R.E.
登録日2008-01-24
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
3DC2
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BU of 3dc2 by Molmil
Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis
分子名称: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID, SERINE
著者Dey, S, Sacchettini, J.C.
登録日2008-06-03
公開日2008-07-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase
Biochemistry, 47, 2008
2QMW
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The crystal structure of the prephenate dehydratase (PDT) from Staphylococcus aureus subsp. aureus Mu50
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Tan, K, Zhang, R, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-07-17
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of open (R) and close (T) states of prephenate dehydratase (PDT) - implication of allosteric regulation by L-phenylalanine.
J.Struct.Biol., 162, 2008

 

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