Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 128 件
4A0K
DownloadVisualize
BU of 4a0k by Molmil
STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
分子名称: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
著者Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
登録日2011-09-09
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (5.93 Å)
主引用文献The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
6R7H
DownloadVisualize
BU of 6r7h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7N
DownloadVisualize
BU of 6r7n by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-29
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7I
DownloadVisualize
BU of 6r7i by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2019-09-04
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
8WQH
DownloadVisualize
BU of 8wqh by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQB
DownloadVisualize
BU of 8wqb by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQG
DownloadVisualize
BU of 8wqg by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.09 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQF
DownloadVisualize
BU of 8wqf by Molmil
cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQC
DownloadVisualize
BU of 8wqc by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQE
DownloadVisualize
BU of 8wqe by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQA
DownloadVisualize
BU of 8wqa by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WDK
DownloadVisualize
BU of 8wdk by Molmil
The complex structure of Cul2-VCB-Protac-Wee1
分子名称: (2S,4R)-1-[(2S)-3,3-dimethyl-2-[3-[4-[4-[4-[[3-oxidanylidene-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]-2-prop-2-enyl-pyrazolo[3,4-d]pyrimidin-6-yl]amino]phenyl]piperazin-1-yl]butoxy]propanoylamino]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Wang, P, Zhang, T.T.
登録日2023-09-15
公開日2024-09-18
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structure of Cul2-VCB-Protac-Wee1 complex at 3.6 Angstrom resolution.
To Be Published
6TNT
DownloadVisualize
BU of 6tnt by Molmil
SUMOylated apoAPC/C with repositioned APC2 WHB domain
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Barford, D, Yatskevich, S.
登録日2019-12-10
公開日2021-01-13
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
6R6H
DownloadVisualize
BU of 6r6h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N.
登録日2019-03-27
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6TM5
DownloadVisualize
BU of 6tm5 by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Barford, D.
登録日2019-12-03
公開日2020-02-19
最終更新日2020-06-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
6TLJ
DownloadVisualize
BU of 6tlj by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Barford, D.
登録日2019-12-02
公開日2020-02-19
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
6TTU
DownloadVisualize
BU of 6ttu by Molmil
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Prabu, J.R, Schulman, B.A.
登録日2019-12-30
公開日2020-02-12
最終更新日2020-03-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
7Z8B
DownloadVisualize
BU of 7z8b by Molmil
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
分子名称: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ...
著者Hopf, L.V.M, Schulman, B.A.
登録日2022-03-17
公開日2022-08-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Nat.Struct.Mol.Biol., 29, 2022
8A5Y
DownloadVisualize
BU of 8a5y by Molmil
S. cerevisiae apo unphosphorylated APC/C.
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
8A61
DownloadVisualize
BU of 8a61 by Molmil
S. cerevisiae apo phosphorylated APC/C
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
8A3T
DownloadVisualize
BU of 8a3t by Molmil
S. cerevisiae APC/C-Cdh1 complex
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
登録日2022-06-09
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
8JE1
DownloadVisualize
BU of 8je1 by Molmil
An asymmetry dimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complexed with BEX2
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-05-15
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
8JE2
DownloadVisualize
BU of 8je2 by Molmil
Cryo-EM structure of neddylated Cul2-Rbx1-EloBC-FEM1B complexed with FNIP1-FLCN
分子名称: Cullin-2, Elongin-B, Elongin-C, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-05-15
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
8KHP
DownloadVisualize
BU of 8khp by Molmil
CULLIN3-KLHL22-RBX1 E3 ligase
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch-like protein 22
著者Su, M.-Y, Su, M.-Y.
登録日2023-08-22
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme.
Structure, 31, 2023
8K8T
DownloadVisualize
BU of 8k8t by Molmil
Structure of CUL3-RBX1-KLHL22 complex
分子名称: Cullin-3, Kelch-like protein 22
著者Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
登録日2023-07-31
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon