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PDB: 659 件
6BXG
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1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
分子名称: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ...
著者Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-12-18
公開日2018-01-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
To Be Published
4UU6
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BU of 4uu6 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
登録日2014-07-24
公開日2015-01-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3ZRT
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BU of 3zrt by Molmil
Crystal structure of human PSD-95 PDZ1-2
分子名称: DISKS LARGE HOMOLOG 4
著者Sorensen, P.L, Kastrup, J.S, Gajhede, M.
登録日2011-06-19
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.398 Å)
主引用文献A High-Affinity, Dimeric Inhibitor of Psd-95 Bivalently Interacts with Pdz1-2 and Protects Against Ischemic Brain Damage.
Proc.Natl.Acad.Sci.USA, 109, 2012
1D5G
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BU of 1d5g by Molmil
SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE
分子名称: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV
著者Kozlov, G, Gehring, K, Ekiel, I.
登録日1999-10-07
公開日2002-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions
J.Mol.Biol., 320, 2002
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
分子名称: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
著者Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
登録日2023-03-11
公開日2023-05-10
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
4N6X
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BU of 4n6x by Molmil
Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1
分子名称: CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein
著者Lu, G, Wu, Y, Jiang, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z.
登録日2013-10-14
公開日2014-01-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.051 Å)
主引用文献New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
5TYT
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Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
分子名称: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera
著者Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z.
登録日2016-11-21
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.
Biochem. Biophys. Res. Commun., 485, 2017
5K4F
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CAL PDZ mutant C319A with a peptide
分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 peptide
著者Zhao, Y, Madden, D.R.
登録日2016-05-20
公開日2017-08-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献CAL PDZ domain mutant with a peptide
To Be Published
8WWR
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Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Omble, A, Mahajan, S, Kulkarni, K.A.
登録日2023-10-26
公開日2024-05-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
8YR7
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BU of 8yr7 by Molmil
Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif
分子名称: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19
著者Omble, A, Mahajan, S, Kulkarni, K.A.
登録日2024-03-20
公開日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
5JXB
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PSD-95 extended PDZ3 in complex with SynGAP PBM
分子名称: Disks large homolog 4,SynGAP
著者Shang, Y, Zhang, M.
登録日2016-05-13
公開日2016-09-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.
Cell, 166, 2016
6SPZ
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BU of 6spz by Molmil
Crystal structure of PDZ1-2 from PSD-95 with peptide ligand sequence RRESEI bound to both domains
分子名称: ARG-ARG-GLU-SER-GLU-ILE, Disks large homolog 4, GLUTATHIONE
著者Rodzli, N, Levy, C.W, Prince, S.M.
登録日2019-09-03
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献The Dual PDZ Domain from Postsynaptic Density Protein 95 Forms a Scaffold with Peptide Ligand.
Biophys.J., 119, 2020
6SPV
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Crystal structure of PDZ1-2 from PSD-95
分子名称: Disks large homolog 4, GLUTATHIONE
著者Rodzli, N, Levy, C.W, Prince, S.M.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The Dual PDZ Domain from Postsynaptic Density Protein 95 Forms a Scaffold with Peptide Ligand.
Biophys.J., 119, 2020
7CQF
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BU of 7cqf by Molmil
Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ...
著者Yamagata, A, Fukai, S.
登録日2020-08-10
公開日2021-01-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.
Proc.Natl.Acad.Sci.USA, 118, 2021
8GI4
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BU of 8gi4 by Molmil
Crystal structure of human LIMK2 PDZ domain
分子名称: LIM domain kinase 2
著者Casanova Sepulveda, G, Boggon, T.J.
登録日2023-03-13
公開日2023-12-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Autoregulation of the LIM kinases by their PDZ domain.
Nat Commun, 14, 2023
8HCK
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BU of 8hck by Molmil
NMR fragment-based screening against the two PDZ do-mains of MDA-9
分子名称: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, GLYCEROL, SULFATE ION, ...
著者Tang, H.
登録日2022-11-01
公開日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献NMR fragment-based screening against the two PDZ do-mains of MDA-9
To Be Published
8HU2
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Rattus Syntenin-1 PDZ domain with inhibitor
分子名称: (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1
著者Heo, Y, Lee, J, Yun, J.H, Lee, W.
登録日2022-12-22
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution.
To Be Published
1BFE
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BU of 1bfe by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
分子名称: PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1B8Q
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SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE
分子名称: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE)
著者Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M.
登録日1999-02-01
公開日1999-04-29
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
Nat.Struct.Biol., 6, 1999
7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
分子名称: PBM, Sorting nexin-27
著者Shang, G.J, Qi, J.X.
登録日2021-01-27
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
1BE9
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BU of 1be9 by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
分子名称: CRIPT, PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
7D6F
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The crystal structure of ARMS-PBM/MAGI2-PDZ4
分子名称: GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ...
著者Ye, J, Zhang, Y, Zhong, Z, Wang, C.
登録日2020-09-30
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode.
Neurochem.Int., 149, 2021
2W4F
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CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1
分子名称: 1,2-ETHANEDIOL, PROTEIN LAP4
著者Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U.
登録日2008-11-25
公開日2008-12-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
2VRF
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CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN
分子名称: 1,2-ETHANEDIOL, BETA-2-SYNTROPHIN
著者Sun, Z, Roos, A.K, Pike, A.C.W, Pilka, E.S, Cooper, C, Elkins, J.M, Murray, J, Arrowsmith, C.H, Doyle, D, Edwards, A, von Delft, F, Bountra, C, Oppermann, U.
登録日2008-03-31
公開日2008-04-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Human Beta-2-Syntrophin Pdz Domain
To be Published
2VPH
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Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain
分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4
著者Roos, A.K, Wang, J, Burgess-Brown, N, Elkins, J.M, Kavanagh, K, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Bountra, C, Knapp, S.
登録日2008-02-29
公開日2008-03-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Human Protein Tyrosine Phosphatase, Non-Receptor Type 4, Pdz Domain
To be Published

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件を2024-06-26に公開中

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