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PDB: 672 件
5K4F
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CAL PDZ mutant C319A with a peptide
分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 peptide
著者Zhao, Y, Madden, D.R.
登録日2016-05-20
公開日2017-08-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献CAL PDZ domain mutant with a peptide
To Be Published
3K82
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Crystal Structure of the third PDZ domain of PSD-95
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disks large homolog 4, GLYCEROL, ...
著者Camara-Artigas, A, Gavira, J.A.
登録日2009-10-13
公開日2010-04-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
7RM8
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BU of 7rm8 by Molmil
Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
分子名称: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
著者Healy, M.D, Collins, B.M, Mobli, M.
登録日2021-07-26
公開日2022-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
2BYG
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2nd PDZ Domain of Discs Large Homologue 2
分子名称: CHANNEL ASSOCIATED PROTEIN OF SYNAPSE-110
著者Elkins, J.M, Schoch, G.A, Smee, C.E.A, Berridge, G, Salah, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2005-08-01
公開日2005-08-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
7XTY
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BU of 7xty by Molmil
Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide
分子名称: APC-peptide, Tyrosine-protein phosphatase non-receptor type 13
著者Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L.
登録日2022-05-18
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
to be published
9F6S
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BU of 9f6s by Molmil
PDZ domain in complex with the peptide from AP2-associated protein kinase 1
分子名称: AP2-associated protein kinase 1, PDZ and LIM domain protein 5
著者Benova, V, Boura, E.
登録日2024-05-02
公開日2025-05-14
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献PDZ domain in complex with the peptide from AP2-associated protein kinase 1
To Be Published
1KEF
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BU of 1kef by Molmil
PDZ1 of SAP90
分子名称: synapse associated protein-90
著者Piserchio, A, Pellegrini, M, Mehta, S, Blackman, S.M, Garcia, E.P, Marshall, J, Mierke, D.F.
登録日2001-11-15
公開日2002-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The PDZ1 domain of SAP90. Characterization of structure and binding.
J.Biol.Chem., 277, 2002
4UU6
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
登録日2014-07-24
公開日2015-01-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
1BE9
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THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
分子名称: CRIPT, PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
4K78
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CFTR Associated Ligand (CAL) E317A PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)
分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide
著者Amacher, J.F, Madden, D.R.
登録日2013-04-16
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
2REY
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BU of 2rey by Molmil
Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh)
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Papagrigoriou, E, Gileadi, C, Elkins, J, Cooper, C, Ugochukwu, E, Turnbull, A, Pike, A.C.W, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
4K75
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CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)
分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide
著者Amacher, J.F, Madden, D.R.
登録日2013-04-16
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4UU5
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
分子名称: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ...
著者Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
登録日2014-07-24
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
7NTJ
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BU of 7ntj by Molmil
PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex
分子名称: Envelope small membrane protein, MAGUK p55 subfamily member 5
著者Javorsky, A, Kvansakul, M.
登録日2021-03-10
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
7NTK
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PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ...
著者Javorsky, A, Kvansakul, M.
登録日2021-03-10
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
2RCZ
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BU of 2rcz by Molmil
Structure of the second PDZ domain of ZO-1
分子名称: Tight junction protein ZO-1
著者Lavie, A, Lye, M.F.
登録日2007-09-20
公開日2007-10-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Domain swapping within PDZ2 is responsible for dimerization of ZO proteins.
J.Biol.Chem., 282, 2007
4WYU
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BU of 4wyu by Molmil
Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide
分子名称: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU
著者Ren, J.Q, Pei, H.H, Feng, W.
登録日2014-11-18
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
8YR7
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BU of 8yr7 by Molmil
Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif
分子名称: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19
著者Omble, A, Mahajan, S, Kulkarni, K.A.
登録日2024-03-20
公開日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
1D5G
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SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE
分子名称: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV
著者Kozlov, G, Gehring, K, Ekiel, I.
登録日1999-10-07
公開日2002-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions
J.Mol.Biol., 320, 2002
5TYT
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Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
分子名称: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera
著者Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z.
登録日2016-11-21
公開日2017-02-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.
Biochem. Biophys. Res. Commun., 485, 2017
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
分子名称: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
著者Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
登録日2023-03-11
公開日2023-05-10
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
1B8Q
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SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE
分子名称: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE)
著者Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M.
登録日1999-02-01
公開日1999-04-29
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
Nat.Struct.Biol., 6, 1999
1BFE
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THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
分子名称: PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
3CBY
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BU of 3cby by Molmil
The Dvl2 PDZ Domain in Complex with the N1 Inhibitory Peptide
分子名称: 1,2-ETHANEDIOL, Dishevelled-2
著者Appleton, B.A, Wiesmann, C.
登録日2008-02-23
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
3CBX
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The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Dishevelled-2
著者Appleton, B.A, Wiesmann, C.
登録日2008-02-23
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009

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