Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 616 件
8P0D
DownloadVisualize
BU of 8p0d by Molmil
Human 14-3-3 sigma in complex with human MDM2 peptide
分子名称: 14-3-3 protein sigma, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Roversi, P, Ward, J, Doveston, R, Kwon, H, Romartinez Alonso, B.
登録日2023-05-10
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Characterizing the protein-protein interaction between MDM2 and 14-3-3 sigma ; proof of concept for small molecule stabilization.
J.Biol.Chem., 300, 2024
2C1J
DownloadVisualize
BU of 2c1j by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-15
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
2BR9
DownloadVisualize
BU of 2br9 by Molmil
14-3-3 Protein Epsilon (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN EPSILON, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Yang, X, Elkins, J.M, Soundararajan, M, Fedorov, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A.
登録日2005-05-03
公開日2005-05-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2BQ0
DownloadVisualize
BU of 2bq0 by Molmil
14-3-3 Protein Beta (Human)
分子名称: 14-3-3 BETA/ALPHA
著者Yang, X, Elkins, J.M, Fedorov, O, Longman, E.J, Sobott, L, Ball, L.J, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A.
登録日2005-04-26
公開日2005-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C63
DownloadVisualize
BU of 2c63 by Molmil
14-3-3 Protein Eta (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN ETA, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Elkins, J.M, Yang, X, Smee, C.E.A, Johansson, C, Sundstrom, M, Edwards, A, Weigelt, J, Arrowsmith, C, Doyle, D.A.
登録日2005-11-07
公開日2005-11-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C74
DownloadVisualize
BU of 2c74 by Molmil
14-3-3 Protein Eta (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN ETA, CITRIC ACID, CONSENSUS PEPTIDE MODE 1 FOR 14-3-3 PROTEINS
著者Elkins, J.M, Yang, X, Smee, C.E.A, Johansson, C, Sundstrom, M, Edwards, A, Weigelt, J, Arrowsmith, C, Doyle, D.A.
登録日2005-11-17
公開日2005-12-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for protein-protein interactions in the 14-3-3 protein family.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
8Q1S
DownloadVisualize
BU of 8q1s by Molmil
Pathogenic mutations of human phosphorylation sites affect protein-protein interactions
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein epsilon, BROMIDE ION, ...
著者Roske, Y, Daumke, O, Rrustemi, T, Selbach, M.
登録日2023-08-01
公開日2024-02-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Pathogenic mutations of human phosphorylation sites affect protein-protein interactions.
Nat Commun, 15, 2024
2C23
DownloadVisualize
BU of 2c23 by Molmil
14-3-3 Protein Beta (Human) in complex with exoenzyme S peptide
分子名称: 14-3-3 BETA/ALPHA, EXOENZYME S PEPTIDE
著者Elkins, J.M, Schoch, G.A, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A.
登録日2005-09-26
公開日2005-09-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
6QDR
DownloadVisualize
BU of 6qdr by Molmil
Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C.
登録日2019-01-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.615 Å)
主引用文献Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
2C1N
DownloadVisualize
BU of 2c1n by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-16
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
8QT5
DownloadVisualize
BU of 8qt5 by Molmil
Crystal structure of Arabidopsis thaliana 14-3-3 isoform lambda in complex with a phosphopeptide from the transcription factor BZR1.
分子名称: 14-3-3-like protein G-BOX factor 14 lambda,Protein BRASSINAZOLE-RESISTANT 1, ACETATE ION
著者Hothorn, M, Obergfell, E.
登録日2023-10-12
公開日2023-10-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis.
Plant Cell.Physiol., 2024
8QTC
DownloadVisualize
BU of 8qtc by Molmil
Crystal structure of Arabidopsis thaliana 14-3-3 omega in complex with a phosphopeptide from the transcription factor BZR1.
分子名称: 14-3-3-like protein GF14 omega, COBALT (II) ION, Protein BRASSINAZOLE-RESISTANT 1, ...
著者Hothorn, M, Obergfell, E.
登録日2023-10-12
公開日2023-11-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis.
Plant Cell.Physiol., 2024
6QK8
DownloadVisualize
BU of 6qk8 by Molmil
Crystal structure of yeast 14-3-3 protein (Bmh1) from Saccharomyces cerevisiae with the Nha1p (yeast Na+/H+ antiporter) 14-3-3 binding motif Ser481
分子名称: Na(+)/H(+) antiporter, Protein BMH1
著者Smidova, A, Obsil, T, Obsilova, V.
登録日2019-01-28
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.917 Å)
主引用文献The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481.
Biochim Biophys Acta Mol Cell Res, 1866, 2019
8QTT
DownloadVisualize
BU of 8qtt by Molmil
Crystal structure of a C-terminally truncated version of Arabidopsis thaliana 14-3-3 omega in complex with a phosphopeptide from the inhibitor protein BKI1.
分子名称: 1,2-ETHANEDIOL, 14-3-3-like protein GF14 omega, BRI1 kinase inhibitor 1, ...
著者Hothorn, M, Obergfell, E.
登録日2023-10-13
公開日2023-11-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis.
Plant Cell.Physiol., 2024
8QTF
DownloadVisualize
BU of 8qtf by Molmil
Crystal structure of a C-terminally truncated version of Arabidopsis thaliana 14-3-3 omega in complex with a phosphopeptide from the transcription factor BZR1.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 14-3-3-like protein GF14 omega, ...
著者Hothorn, M, Obergfell, E.
登録日2023-10-12
公開日2023-11-22
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis.
Plant Cell.Physiol., 2024
6QHM
DownloadVisualize
BU of 6qhm by Molmil
14-3-3 sigma with RelA/p65 binding site pS281
分子名称: 14-3-3 protein sigma, LEU-SEP-GLU
著者Wolter, M, Ottmann, C.
登録日2019-01-16
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products.
J.Am.Chem.Soc., 142, 2020
6QDT
DownloadVisualize
BU of 6qdt by Molmil
Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C.
登録日2019-01-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
2BTP
DownloadVisualize
BU of 2btp by Molmil
14-3-3 Protein Theta (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN TAU, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Elkins, J.M, Johansson, A.C.E, Smee, C, Yang, X, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2005-06-05
公開日2005-06-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
6QDS
DownloadVisualize
BU of 6qds by Molmil
Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide stabilized by semi-synthetic fusicoccane FC-NCPC
分子名称: 14-3-3 protein sigma, CHLORIDE ION, FC-NCPC, ...
著者Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C.
登録日2019-01-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
4HKC
DownloadVisualize
BU of 4hkc by Molmil
14-3-3-zeta in complex with S1011 phosphorylated integrin alpha-4 peptide
分子名称: 14-3-3 protein zeta/delta, GLYCEROL, alpha-4 integrin derived phosphorylated peptide
著者Bonet, R, Campbell, I.D.
登録日2012-10-15
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Characterization of 14-3-3-zeta Interactions with integrin tails
J.Mol.Biol., 425, 2013
3O8I
DownloadVisualize
BU of 3o8i by Molmil
Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment
分子名称: 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one
著者Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P.
登録日2010-08-03
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling
Mol.Cell.Biol., 30, 2010
4FJ3
DownloadVisualize
BU of 4fj3 by Molmil
14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide
分子名称: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase
著者Ottmann, C, Molzan, M.
登録日2012-06-11
公開日2012-09-05
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer
J.Mol.Biol., 423, 2012
4GNT
DownloadVisualize
BU of 4gnt by Molmil
Complex of ChREBP and 14-3-3beta
分子名称: 14-3-3 protein beta/alpha, Carbohydrate-responsive element-binding protein, SULFATE ION
著者Zhang, H, Huang, N.
登録日2012-08-17
公開日2012-10-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal Structure of Carbohydrate Response Element Binding Protein (ChREBP) in complex with 14-3-3b
To be Published
3P1S
DownloadVisualize
BU of 3p1s by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer fusicoccin A
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1R
DownloadVisualize
BU of 3p1r by Molmil
Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013

223790

件を2024-08-14に公開中

PDB statisticsPDBj update infoContact PDBjnumon