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6QDR

Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide

Summary for 6QDR
Entry DOI10.2210/pdb6qdr/pdb
Descriptor14-3-3 protein sigma, Serine/threonine-protein kinase PAK 6, CALCIUM ION, ... (7 entities in total)
Functional Keywordsneuron regeneration, ppi, phosphorylation, chaperone
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight28049.16
Authors
Andrei, S.A.,Kaplan, A.,Fournier, A.E.,Ottman, C. (deposition date: 2019-01-02, release date: 2020-01-29, Last modification date: 2024-01-24)
Primary citationKaplan, A.,Andrei, S.A.,van Regteren Altena, A.,Simas, T.,Banerjee, S.L.,Kato, N.,Bisson, N.,Higuchi, Y.,Ottmann, C.,Fournier, A.E.
Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27:657-667.e6, 2020
Cited by
PubMed: 32220335
DOI: 10.1016/j.chembiol.2020.02.010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.615 Å)
Structure validation

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