6QDR

Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	14-3-3 protein sigma	polymer	236	26542.9	1	UniProt (P31947) Pfam (PF00244) In PDB	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin
2	B	Serine/threonine-protein kinase PAK 6	polymer	12	1297.4	1	UniProt (Q9NQU5) In PDB	Homo sapiens	PAK-5,p21-activated kinase 6,PAK-6
3	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	A	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
7		water	water		18.0	426	Chemie (HOH)

Sequence modifications

A: 1 - 231 (UniProt: P31947)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 93 - 104 (UniProt: Q9NQU5)

PDB	External Database	Details
Ace 93	Ser 93	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27840.3
Non-Polymers*	Number of molecules	7
	Total formula weight	208.9
All*	Total formula weight	28049.2

*Water molecules are not included.