2QE3
| Crystal structure of human tl1a extracellular domain | 分子名称: | CHLORIDE ION, TNF superfamily ligand TL1A | 著者 | Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | 登録日 | 2007-06-22 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain. Biochemistry, 48, 2009
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2QDN
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6MKB
| Crystal structure of murine 4-1BB ligand | 分子名称: | SODIUM ION, SULFATE ION, Tumor necrosis factor ligand superfamily member 9, ... | 著者 | Bitra, A, Zajonc, D.M, Doukov, T. | 登録日 | 2018-09-25 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding. J. Biol. Chem., 294, 2019
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6MGE
| Structure of human 4-1BBL | 分子名称: | GLYCEROL, PHOSPHATE ION, Tumor necrosis factor ligand superfamily member 9 | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | 登録日 | 2018-09-13 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
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6D3N
| Crystal structure of h4-1BB ligand | 分子名称: | GLYCEROL, Tumor necrosis factor ligand superfamily member 9 | 著者 | Aruna, B, Zajonc, D.M, Doukov, T. | 登録日 | 2018-04-16 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. J. Biol. Chem., 293, 2018
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4KG8
| Crystal structure of light mutant | 分子名称: | Tumor necrosis factor ligand superfamily member 14 | 著者 | Liu, W, Zhan, C, Kumar, P.R, Bonanno, J.B, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | 登録日 | 2013-04-28 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22, 2014
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6OOY
| Asymmetric hTNF-alpha | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Tumor necrosis factor, {1-[(2,5-dimethylphenyl)methyl]-1H-benzimidazol-2-yl}methanol | 著者 | Arakaki, T.L, Edwards, T.E, Ceska, T. | 登録日 | 2019-04-23 | 公開日 | 2019-12-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun, 10, 2019
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2RJK
| Crystal Structure of Human TL1A Extracellular Domain C95S Mutant | 分子名称: | TNF superfamily ligand TL1A | 著者 | Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Ramagopal, U.A, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | 登録日 | 2007-10-15 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain. Biochemistry, 48, 2009
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2TNF
| 1.4 A RESOLUTION STRUCTURE OF MOUSE TUMOR NECROSIS FACTOR, TOWARDS MODULATION OF ITS SELECTIVITY AND TRIMERISATION | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ISOPROPYL ALCOHOL, PROTEIN (TUMOR NECROSIS FACTOR ALPHA) | 著者 | Baeyens, K.J, De Bondt, H.L, Raeymaekers, A, Fiers, W, De Ranter, C.J. | 登録日 | 1998-10-12 | 公開日 | 1999-10-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization. Acta Crystallogr.,Sect.D, 55, 1999
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2RE9
| Crystal structure of TL1A at 2.1 A | 分子名称: | GLYCEROL, MAGNESIUM ION, TNF superfamily ligand TL1A | 著者 | Jin, T.C, Guo, F, Kim, S, Howard, A.J, Zhang, Y.Z. | 登録日 | 2007-09-25 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystal structure of TNF ligand family member TL1A at 2.1 A. Biochem.Biophys.Res.Commun., 364, 2007
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2RJL
| Crystal structure of human TL1A extracellular domain C95S/C135S mutant | 分子名称: | TNF superfamily ligand TL1A | 著者 | Zhan, C, Patskovsky, Y, Yan, Q, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C. | 登録日 | 2007-10-15 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Biochemical and structural characterization of the human TL1A ectodomain. Biochemistry, 48, 2009
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1IQA
| CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND | 分子名称: | RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND | 著者 | Ito, S, Wakabayashi, K, Ubukata, O, Hayashi, S, Okada, F, Hata, T. | 登録日 | 2001-07-11 | 公開日 | 2002-03-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution. J.Biol.Chem., 277, 2002
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2TUN
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1KXG
| The 2.0 Ang Resolution Structure of BLyS, B Lymphocyte Stimulator. | 分子名称: | 1,4-DIETHYLENE DIOXIDE, B lymphocyte stimulator, CITRIC ACID, ... | 著者 | Oren, D.A, Li, Y, Volovik, Y, Morris, T.S, Dharia, C, Das, K, Galperina, O, Gentz, R, Arnold, E. | 登録日 | 2002-01-31 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of BLyS receptor recognition. Nat.Struct.Biol., 9, 2002
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1KD7
| Crystal structure of an extracellular domain fragment of human BAFF | 分子名称: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B | 著者 | Karpusas, M, Cachero, T.G, Qian, F, Boriack-Sjodin, A, Mullen, C, Strauch, K, Hsu, Y.-M, Kalled, S.L. | 登録日 | 2001-11-12 | 公開日 | 2002-11-12 | 最終更新日 | 2017-02-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Extracellular Human BAFF, a TNF Family Member that Stimulates B Lymphocytes J.Mol.Biol., 315, 2002
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2X29
| Crystal structure of human4-1BB ligand ectodomain | 分子名称: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 | 著者 | Won, E.Y, Cho, H.S. | 登録日 | 2010-01-12 | 公開日 | 2010-03-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Structure of the Trimer of Human 4-1Bb Ligand is Unique Among Members of the Tumor Necrosis Factor Superfamily. J.Biol.Chem., 285, 2010
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1I9R
| STRUCTURE OF CD40L IN COMPLEX WITH THE FAB FRAGMENT OF HUMANIZED 5C8 ANTIBODY | 分子名称: | CD40 LIGAND, IMMUNOGLOBULIN H, IMMUNOGLOBULIN L, ... | 著者 | Karpusas, M, Lucci, J, Ferrant, J, Benjamin, C, Hsu, Y.-M. | 登録日 | 2001-03-20 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody. Structure, 9, 2001
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1JH5
| Crystal Structure of sTALL-1 of TNF family ligand | 分子名称: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B | 著者 | Liu, Y, Xu, L, Opalka, N, Shu, H.-B, Zhang, G. | 登録日 | 2001-06-27 | 公開日 | 2002-02-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell(Cambridge,Mass.), 108, 2002
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1JTZ
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1ALY
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1A8M
| TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT | 分子名称: | TUMOR NECROSIS FACTOR ALPHA | 著者 | Reed, C, Fu, Z.-Q, Wu, J, Xue, Y.-N, Harrison, R.W, Chen, M.-J, Weber, I.T. | 登録日 | 1998-03-27 | 公開日 | 1998-06-17 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2. Protein Eng., 10, 1997
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1D2Q
| CRYSTAL STRUCTURE OF HUMAN TRAIL | 分子名称: | TNF-RELATED APOPTOSIS INDUCING LIGAND | 著者 | Cha, S.-S. | 登録日 | 1999-09-27 | 公開日 | 2000-02-11 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity, 11, 1999
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1DG6
| CRYSTAL STRUCTURE OF APO2L/TRAIL | 分子名称: | APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL), CHLORIDE ION, ZINC ION | 著者 | Hymowitz, S.G, O'ConnelL, M.P, Ultsch, M.H, de Vos, A.M, Kelley, R.F. | 登録日 | 1999-11-23 | 公開日 | 2000-01-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry, 39, 2000
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1U5Y
| Crystal structure of murine APRIL, pH 8.0 | 分子名称: | Tumor necrosis factor ligand superfamily member 13 | 著者 | Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G. | 登録日 | 2004-07-28 | 公開日 | 2004-10-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Crystal Structure of A Proliferation-inducing Ligand, APRIL. J.Mol.Biol., 343, 2004
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1U5Z
| The Crystal structure of murine APRIL, pH 8.5 | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13 | 著者 | Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G. | 登録日 | 2004-07-28 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of A Proliferation-inducing Ligand, APRIL. J.Mol.Biol., 343, 2004
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