1IQA

CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND

Summary for 1IQA

Entry DOI	10.2210/pdb1iqa/pdb
Descriptor	RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND (2 entities in total)
Functional Keywords	homotrimer, beta-strand jellyroll, rankl, rank ligand, rank, cytokine, tnf, bone remodeling, osteoclast differentiation factor
Biological source	Mus musculus (house mouse)
Cellular location	Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235
Total number of polymer chains	3
Total formula weight	54002.06
Authors	Ito, S.,Wakabayashi, K.,Ubukata, O.,Hayashi, S.,Okada, F.,Hata, T. (deposition date: 2001-07-11, release date: 2002-03-13, Last modification date: 2023-12-27)
Primary citation	Ito, S.,Wakabayashi, K.,Ubukata, O.,Hayashi, S.,Okada, F.,Hata, T. Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution. J.Biol.Chem., 277:6631-6636, 2002 Cited by PubMed: 11733492 DOI: 10.1074/jbc.M106525200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation