6MKB

Crystal structure of murine 4-1BB ligand

Summary for 6MKB

Entry DOI	10.2210/pdb6mkb/pdb
Descriptor	Tumor necrosis factor ligand superfamily member 9, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	tnf, signaling protein, dimer
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	80935.76
Authors	Bitra, A.,Zajonc, D.M.,Doukov, T. (deposition date: 2018-09-25, release date: 2018-12-19, Last modification date: 2023-10-11)
Primary citation	Bitra, A.,Doukov, T.,Destito, G.,Croft, M.,Zajonc, D.M. Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding. J. Biol. Chem., 294:1831-1845, 2019 Cited by PubMed: 30545939 DOI: 10.1074/jbc.RA118.006297 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation