1POU
| THE SOLUTION STRUCTURE OF THE OCT-1 POU-SPECIFIC DOMAIN REVEALS A STRIKING SIMILARITY TO THE BACTERIOPHAGE LAMBDA REPRESSOR DNA-BINDING DOMAIN | 分子名称: | OCT-1 | 著者 | Assa-Munt, N, Mortishire-Smith, R.J, Aurora, R, Herr, W, Wright, P.E. | 登録日 | 1993-06-14 | 公開日 | 1994-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain. Cell(Cambridge,Mass.), 73, 1993
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6T90
| OCT4-SOX2-bound nucleosome - SHL-6 | 分子名称: | DNA (146-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-10-25 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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6HT5
| Oct4/Sox2:UTF1 structure | 分子名称: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ... | 著者 | Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M. | 登録日 | 2018-10-03 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.451 Å) | 主引用文献 | Oct4/Sox2:UTF1 structure To Be Published
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7XRC
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6YOV
| OCT4-SOX2-bound nucleosome - SHL+6 | 分子名称: | DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2020-04-15 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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2XSD
| Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', ... | 著者 | Jauch, R, Choo, S.H, Ng, C.K.L, Kolatkar, P.R. | 登録日 | 2010-09-28 | 公開日 | 2010-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA. Proteins, 79, 2011
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1AU7
| PIT-1 MUTANT/DNA COMPLEX | 分子名称: | CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1 | 著者 | Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K. | 登録日 | 1997-09-12 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes Dev., 11, 1997
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8OTS
| OCT4 and MYC-MAX co-bound to a nucleosome | 分子名称: | DNA (127-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. | 登録日 | 2023-04-21 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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5WC9
| Human Pit-1 and 4xCATT DNA complex | 分子名称: | DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3'), Pituitary-specific positive transcription factor 1 | 著者 | Agarwal, S, Cho, T.Y. | 登録日 | 2017-06-29 | 公開日 | 2017-11-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter. Nucleic Acids Res., 46, 2018
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3L1P
| POU protein:DNA complex | 分子名称: | DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ... | 著者 | Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M. | 登録日 | 2009-12-14 | 公開日 | 2010-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A unique Oct4 interface is crucial for reprogramming to pluripotency Nat.Cell Biol., 15, 2013
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3D1N
| Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter | 分子名称: | 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ... | 著者 | Pereira, J.H, Ha, S.C, Kim, S.-H. | 登録日 | 2008-05-06 | 公開日 | 2009-05-26 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of human Brn-5 transcription factor in complex with CRH gene promoter. J.Struct.Biol., 167, 2009
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8SPS
| High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b | 分子名称: | DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2023-05-03 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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8SPU
| Structure of ESRRB nucleosome bound OCT4 at site c | 分子名称: | DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2023-05-03 | 公開日 | 2023-06-28 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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7U0G
| structure of LIN28b nucleosome bound 3 OCT4 | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2022-02-18 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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7U0I
| Structure of LIN28b nucleosome bound 2 OCT4 | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Tengfei, L, Guan, R, Bai, Y. | 登録日 | 2022-02-18 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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1HF0
| Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer | 分子名称: | DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1 | 著者 | Remenyi, A, Tomilin, A, Pohl, E, Scholer, H.R, Wilmanns, M. | 登録日 | 2000-11-27 | 公開日 | 2001-11-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping Mol.Cell, 8, 2001
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1CQT
| CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT | 分子名称: | DNA (5'-D(*AP*CP*CP*TP*TP*AP*TP*TP*TP*GP*CP*AP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*GP*CP*AP*AP*AP*TP*AP*AP*GP*G)-3'), POU DOMAIN, ... | 著者 | Chasman, D.I, Cepek, K, Sharp, P.A, Pabo, C.O. | 登録日 | 1999-08-11 | 公開日 | 1999-11-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes Dev., 13, 1999
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1GT0
| Crystal structure of a POU/HMG/DNA ternary complex | 分子名称: | 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ... | 著者 | Remenyi, A, Wilmanns, M. | 登録日 | 2002-01-09 | 公開日 | 2003-01-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers Genes Dev., 17, 2003
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1E3O
| Crystal structure of Oct-1 POU dimer bound to MORE | 分子名称: | 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*A)-3', 5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*T)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1 | 著者 | Remenyi, A, Tomilin, A, Pohl, E, Schoeler, H, Wilmanns, M. | 登録日 | 2000-06-20 | 公開日 | 2001-11-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping Mol.Cell, 8, 2001
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8BX1
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8BX2
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1O4X
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1OCT
| CRYSTAL STRUCTURE OF THE OCT-1 POU DOMAIN BOUND TO AN OCTAMER SITE: DNA RECOGNITION WITH TETHERED DNA-BINDING MODULES | 分子名称: | DNA (5'-D(*AP*CP*CP*TP*TP*AP*TP*TP*TP*GP*CP*AP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*GP*CP*AP*AP*AP*TP*AP*AP*GP*G)-3'), PROTEIN (OCT-1 POU DOMAIN) | 著者 | Klemm, J.D, Rould, M.A, Aurora, R, Herr, W, Pabo, C.O. | 登録日 | 1994-05-09 | 公開日 | 1994-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell(Cambridge,Mass.), 77, 1994
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8G88
| Human Oct4 bound to nucleosome with human nMatn1 sequence | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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8G87
| Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region) | 分子名称: | POU domain, class 5, transcription factor 1, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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