1HF0

Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer

Summary for 1HF0

Related1CQT 1E3O
DescriptorOCTAMER-BINDING TRANSCRIPTION FACTOR 1, DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', ... (4 entities in total)
Functional Keywordstranscription, oct-1, pou domain, dimer
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight50157.36
Authors
Remenyi, A.,Tomilin, A.,Pohl, E.,Scholer, H.R.,Wilmanns, M. (deposition date: 2000-11-27, release date: 2001-11-10, Last modification date: 2019-07-24)
Primary citation
Remenyi, A.,Tomilin, A.,Pohl, E.,Lins, K.,Philippsen, A.,Reinbold, R.,Scholer, H.R.,Wilmanns, M.
Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8:569-, 2001
PubMed: 11583619 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(01)00336-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers22 4.4% 7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-23