1HF0

Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. IAdqLnMEkeVIRVWFsNrrqkeK

Chain	Residue	Details
A	ILE134-LYS157

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site_id	PS00035
Number of Residues	13
Details	POU_1 POU-specific (POUs) domain signature 1. RRIkLGFtQgDVG

Chain	Residue	Details
A	ARG19-GLY31

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site_id	PS00465
Number of Residues	14
Details	POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLnLS

Chain	Residue	Details
A	SER43-SER56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	ARG100-ASN160
B	ARG100-ASN160

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER4
B	SER4

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:1684878

Chain	Residue	Details
A	SER107
B	SER107

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